Results 171 to 180 of about 5,216,846 (353)

Uniquome: Construction and decoding of a novel proteomic atlas that contains new peptide entities

open access: yesComputational and Structural Biotechnology Journal
Cellular and molecular uniqueness have recently gained eminent importance due to the large amount of data produced by the use of “omics” technologies.
Evangelos Kontopodis   +5 more
doaj   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

open access: yesAdvanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou   +11 more
wiley   +1 more source

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2004
J. Syka   +4 more
semanticscholar   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato   +9 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Bioinformatics Designing of 10-23 Deoxyribozyme against Coding Region of Beta-galactosidase Gene

open access: yesResearch in Molecular Medicine, 2017
Background: Deoxyribozymes (Dzs) can play a role as gene expression inhibitors at mRNA level. Among Dzs, the 10-23 deoxyribozyme has significant potentials for treatment of diseases.
Nasrin al-Sadat Ahmadi   +2 more
doaj  

A Paired Database of Predicted and Experimental Protein Peptide Binding Information

open access: yesScientific Data
Peptides are important biomolecules, and their interactions with proteins make them useful in sensing and therapeutic applications. Computational peptide design methods can benefit from high-quality peptide-protein structures paired with thermodynamic ...
Jazmine A. Torres   +2 more
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

open access: yesAdvanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv   +10 more
wiley   +1 more source

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