Results 191 to 200 of about 4,153,258 (343)

Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. [PDF]

PLoS One, 2020
Tackenberg C, Kulic L, Nitsch RM.
europepmc   +1 more source

sequencing of peptides and proteins

, 2008
Noga, Marek, Dyląg, Tomasz, Silberring, Jerzy   +2 more
openaire   +3 more sources

Machine Learning Guided Design of Nerve‐On‐A‐Chip Platforms with Promoted Neurite Outgrowth

Advanced Functional Materials, EarlyView.
Compared to labor‐intensive trial‐and‐error experimentation, a machine learning (ML)‐guided workflow, incorporating cell viability assays, data augmentation, ensemble modeling, and model interpretation, is developed to accelerate nerve‐on‐a‐chip optimization and uncover data‐driven design principles.
Tsai‐Chun Chung, Chu‐Chun Liang, Min‐Wei Huang, Tianle Chen, Joshua M. Little, Snehi Shrestha, Yi‐Chen Ethan Li, I‐Chi Lee, Po‐Yen Chen   +8 more
wiley   +1 more source

The Hunt Lab Guide to De Novo Peptide Sequence Analysis by Tandem Mass Spectrometry. [PDF]

Mol Cell Proteomics
Anderson LC, Bai DL, Blakney GT, Butcher DS, Reser L, Shabanowitz J.   +5 more
europepmc   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Peptipedia v2.0: a peptide sequence database and user-friendly web platform. A major update. [PDF]

Database (Oxford)
Cabas-Mora G, Daza A, Soto-García N, Garrido V, Alvarez D, Navarrete M, Sarmiento-Varón L, Sepúlveda Yañez JH, Davari MD, Cadet F, Olivera-Nappa Á, Uribe-Paredes R, Medina-Ortiz D.   +12 more
europepmc   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Deep Learning Predicts Non-Normal Transmission Distributions in High-Field Asymmetric Waveform Ion Mobility (FAIMS) Directly from Peptide Sequence. [PDF]

Anal Chem
McKetney J, Miller IJ, Hutton A, Sinitcyn P, Serrano LR, Coon JJ, Meyer JG.   +6 more
europepmc   +1 more source

The Amino Acid Sequence of Peptide (1–24) of Rat and Human Serum Albumins

, 1969
Ralph Bradshaw, Theodore Peters
openalex   +1 more source

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

Advanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue, Tetsushi Taguchi, Taka‐Aki Asoh, Akihiro Nishiguchi   +3 more
wiley   +1 more source