Results 221 to 230 of about 1,077,842 (362)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

Advanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling, Stephanie Eitner, Davide Bottone, Gea Cereghetti, Peter Wick   +4 more
wiley   +1 more source

Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. [PDF]

PLoS One, 2020
Tackenberg C, Kulic L, Nitsch RM.
europepmc   +1 more source

The Amino Acid Sequence of Peptide (1–24) of Rat and Human Serum Albumins

, 1969
Ralph Bradshaw, Theodore Peters
openalex   +1 more source

sequencing of peptides and proteins

, 2008
Noga, Marek, Dyląg, Tomasz, Silberring, Jerzy   +2 more
openaire   +3 more sources

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

Advanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer, Adriana Vilaça, Miguel Xavier, Rafael Santos, Ariel Ionescu, María Lázaro, Victoria Leiro, Eran Perlson, Sofia C. Guimarães, Ben M. Maoz, Ana P. Pêgo   +10 more
wiley   +1 more source

The Hunt Lab Guide to De Novo Peptide Sequence Analysis by Tandem Mass Spectrometry. [PDF]

Mol Cell Proteomics
Anderson LC, Bai DL, Blakney GT, Butcher DS, Reser L, Shabanowitz J.   +5 more
europepmc   +1 more source

Nanomaterial‐Enhanced Biosensing: Mechanisms and Emerging Applications

Advanced Healthcare Materials, EarlyView.
Nanomaterial integration transforms biosensor capabilities through enhanced signal transduction, sensitivity, and selectivity. This review analyzes how nanoscale materials—from nanoparticles to nanosheets—leverage unique physicochemical properties to revolutionize electrochemical, optical, and electrical biosensing.
Younghak Cho, Yunyoung Choi, Yerim Jang, Hyejeong Seong   +3 more
wiley   +1 more source

Peptipedia v2.0: a peptide sequence database and user-friendly web platform. A major update. [PDF]

Database (Oxford)
Cabas-Mora G, Daza A, Soto-García N, Garrido V, Alvarez D, Navarrete M, Sarmiento-Varón L, Sepúlveda Yañez JH, Davari MD, Cadet F, Olivera-Nappa Á, Uribe-Paredes R, Medina-Ortiz D.   +12 more
europepmc   +1 more source