Results 281 to 290 of about 795,931 (315)
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Mass spectrometric peptide sequencing: Cyclochlorotine
Biological Mass Spectrometry, 1979A potent toxin isolated from Penicillium islandicum Sopp was found to have the composition C24H31N5O7Cl2. Mass spectrometric investigation of a partial acid hydrolyzate showed that it has the structure of cyclochlorotine. The mass spectral characteristics of polyamino alcohol-related derivatives of peptides containing beta-phenylalanine, alpha-amino ...
R J, Anderegg +3 more
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Microfluidic Superheating for Peptide Sequence Elucidation
Analytical Chemistry, 2015Herein, we introduce microfluidic superheating as a new method for peptide fragmentation prior to mass spectrometric analysis. The superheating conditions were found to be stable up to 240 °C for more than 30 min without elevated pressure or boiling of the aqueous sample. As proof of principle, we exposed the peptides ACTH1-10 and OVA257-264 to various
Matthias O, Altmeyer +2 more
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Sequence generation in prebiological peptide synthesis
Archives of Biochemistry and Biophysics, 1967Abstract In contradistinction to the suggestion that peptide synthesis occurring nonenzymically on the primitive Earth would be a totally random event, evidence is presented that the interaction of any one given amino acid with another follows well-defined statistics based on the relative reactivity of each amino acid. The effects of environment, pH,
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Polypeptide Helices in Hybrid Peptide Sequences
Journal of the American Chemical Society, 2005A new class of polypeptide helices in hybrid sequences containing alpha-, beta-, and gamma-residues is described. The molecular conformations in crystals determined for the synthetic peptides Boc-Leu-Phe-Val-Aib-betaPhe-Leu-Phe-Val-OMe 1 (betaPhe: (S)-beta3-homophenylalanine) and Boc-Aib-Gpn-Aib-Gpn-OMe 2(Gpn: 1-(aminomethyl)cyclohexaneacetic acid ...
Ananda, Kuppanna +5 more
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On the predictive recognition of signal peptide sequences
Virus Research, 1985DNA sequence analysis of the short unique regions in the genomes of herpes simplex virus (HSV), types 1 and 2, has previously shown that within this region there are four genes, designated US2, US4, US5 and US7, whose functions are unknown but whose predicted amino sequences exhibit hydrophobic N-termini (D.J. McGeoch et al., 1985, J. Mol. Biol. 181, 1-
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Peptimmunology: Immunogenic Peptides and Sequence Redundancy
Current Drug Discovery Technologies, 2005Using short peptide fragments of proteins to elicit antibodies able to recognize the protein from which the peptide sequence was derived, is one of the main goals in immunotherapy today. Indeed, peptide-immunotherapy appears as an obliged way to obtain antibodies of predetermined specificity and exempt from the complications associated with whole cells/
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Mining for antimicrobial peptides in sequence space
Nature Biomedical Engineering, 2023Fangping Wan, Cesar de la Fuente-Nunez
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Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
Cell, 2019Nicolas J Lehrbach +2 more
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