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A Selective History of Protein Sequencing and the Impact of Donald F. Hunt on Protein Sequencing by Tandem Mass Spectrometry. [PDF]
J Proteome ResYates JR.
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Sequence‐assisted peptide synthesis (SAPS)
Chemical Biology and Drug Design, 1998Abstract:In solid‐phase peptide synthesis (SPPS) the growing peptide chain may undergo chain aggregation which can cause serious synthetic problems. A number of investigations concerning this problem have been reported in the chemical literature. During a study of such “difficult sequences” using the Fmoc‐protection strategy, we have observed that ...
Due Larsen, B., Holm, A.
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Bioinformatics, 1986
A computer program has been devised to automate rationalization of peptide fragmentation patterns. The program systematically generates all possible linear amino acid sequences which might be attributable to a peptide with a known amino acid composition.
C. W. Hamm, W. E. Wilson, D. J. Harvan
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A computer program has been devised to automate rationalization of peptide fragmentation patterns. The program systematically generates all possible linear amino acid sequences which might be attributable to a peptide with a known amino acid composition.
C. W. Hamm, W. E. Wilson, D. J. Harvan
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Error-Tolerant Identification of Peptides in Sequence Databases by Peptide Sequence Tags
Analytical Chemistry, 1994We demonstrate a new approach to the identification of mass spectrometrically fragmented peptides. A fragmentation spectrum usually contains a short, easily identifiable series of sequence ions, which yields a partial sequence. This partial sequence divides the peptide into three parts-regions 1, 2, and 3-characterized by the added mass m1 of region 1,
Mann, M, Wilm, M
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The abc's (and xyz's) of peptide sequencing
Nature Reviews Molecular Cell Biology, 2004Proteomics is an increasingly powerful and indispensable technology in molecular cell biology. It can be used to identify the components of small protein complexes and large organelles, to determine post-translational modifications and in sophisticated functional screens.
Hanno, Steen, Matthias, Mann
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A method of peptide sequencing
Journal of the Chemical Society, Chemical Communications, 1973Sequencing of peptides has been carried out by degrading them to diketopiperazines and identification of the diketopiperazine by g.c./m.s. methods.
Robert A. W. Johnstone +2 more
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Matching Peptide Sequences with Mass Spectra
2005We study a method of mapping both mass spectra and sequences to feature vectors and the correlation between them. The method of calculating the feature vector from mass spectra is presented, together with a method for representing sequences. A correlation metric comparing both representations is studied.
Lau, K. W. +3 more
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A model of random sequences for de novo peptide sequencing
Third IEEE Symposium on Bioinformatics and Bioengineering, 2003. Proceedings., 2003We present a model for the probability of random sequences appearing in product ion spectra obtained from tandem mass spectrometry experiments using collision-induced dissociation. We demonstrate the use of these probabilities for ranking candidate peptide sequences obtained using a de novo algorithm.
Kenneth D. Jarman +3 more
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