Results 321 to 330 of about 1,149,411 (357)

Preprocessing peptide sequences for multivariate sequence-property analysis

Chemometrics and Intelligent Laboratory Systems, 1998
Abstract The increasing number of peptide sequences with different lengths, available from synthesised peptide libraries and sequenced proteins are potentially valuable for evaluating structure–activity relationships. However, in order to apply multivariate classification or Quantitative Structure–Activity Relationship (QSAR) analyses on such ...
Per M. Andersson, Michael Sjöström, Torbjörn Lundstedt   +2 more
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Sequence generation in prebiological peptide synthesis

Archives of Biochemistry and Biophysics, 1967
Abstract In contradistinction to the suggestion that peptide synthesis occurring nonenzymically on the primitive Earth would be a totally random event, evidence is presented that the interaction of any one given amino acid with another follows well-defined statistics based on the relative reactivity of each amino acid. The effects of environment, pH,
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Peptimmunology: Immunogenic Peptides and Sequence Redundancy

Current Drug Discovery Technologies, 2005
Using short peptide fragments of proteins to elicit antibodies able to recognize the protein from which the peptide sequence was derived, is one of the main goals in immunotherapy today. Indeed, peptide-immunotherapy appears as an obliged way to obtain antibodies of predetermined specificity and exempt from the complications associated with whole cells/
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Peptide sequencing

Nature Nanotechnology, 2021
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The Dansyl-Edman Method for Peptide Sequencing

1986
The dansyl-Edman method for peptide sequencing uses the Edman degradation (see Chapter 26 ) to sequentially remove amino acids from the N-terminus of a peptide. Following the cleavage step of the Edman degradation, the thiazolinone derivative is extracted with an organic solvent and discarded.
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Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Hierarchical Nanomaterials Assembled from Peptoids and Other Sequence-Defined Synthetic Polymers

Chemical Reviews, 2021
Zhiliang Li, Bin Cai, Wenchao Yang
exaly  

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

Nucleic Acids Research, 2022
Mihaly Varadi, Mandar Deshpande, Oana Stroe   +2 more
exaly  

Protein and Peptide Sequence Determination

1983
In 1950 Edman published a chemical method for the stepwise removal of amino acids from the N-terminus of a peptide.1 This series of reactions has come to be known as the Edman Degradation, and although modifications of this technique have been introduced from time to time, (see below) the Edman Degradation remains, thirty years after its introduction ...
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