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Inhibition of peptide amyloid formation by cationic peptides with homologous sequences

Bioorganic & Medicinal Chemistry Letters, 2003
We have studied the model peptides that undergo self-initiated structural transition from alpha-helix to beta-sheet and self-assembling into amyloid fibrils. We here constructed an inhibition system of amyloid formation utilizing homologous recognition and assembly of peptides with increased solubility.
T. Yamashita   +3 more
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Protein and Peptide Sequence Determination

1983
In 1950 Edman published a chemical method for the stepwise removal of amino acids from the N-terminus of a peptide.1 This series of reactions has come to be known as the Edman Degradation, and although modifications of this technique have been introduced from time to time, (see below) the Edman Degradation remains, thirty years after its introduction ...
openaire   +2 more sources

Proteases in Peptide Mapping and Sequencing

1999
The ability of some proteases to cleave polypeptide chains at restricted cleavage sites makes them important tools for the elucidation of the primary and even higher-order structure of proteins. This chapter provides an introduction into the methodology of enzymatic protein fragmentation.
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On the predictive recognition of signal peptide sequences

Virus Research, 1985
DNA sequence analysis of the short unique regions in the genomes of herpes simplex virus (HSV), types 1 and 2, has previously shown that within this region there are four genes, designated US2, US4, US5 and US7, whose functions are unknown but whose predicted amino sequences exhibit hydrophobic N-termini (D.J. McGeoch et al., 1985, J. Mol. Biol. 181, 1-
openaire   +3 more sources

Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning

Nature Methods, 2019
Siegfried Gessulat   +14 more
semanticscholar   +1 more source

Deep learning enables de novo peptide sequencing from data-independent-acquisition mass spectrometry

Nature Methods, 2018
Ngoc Hieu Tran   +8 more
semanticscholar   +1 more source

A sequence‐function analysis of the silica precipitating silaffin R5 peptide

Journal of Peptide Science, 2014
Carolin C. Lechner   +1 more
semanticscholar   +1 more source

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