Sequence homology between HLA-bound cytomegalovirus and human peptides: A potential trigger for alloreactivity. [PDF]
PLoS ONE, 2017 Human cytomegalovirus (hCMV) reactivation may often coincide with the development of graft-versus-host-disease (GVHD) in stem cell transplantation (SCT).
Charles E Hall +11 more
doaj +1 more source
A Dynamic Programming Approach to De Novo Peptide Sequencing via Tandem Mass Spectrometry [PDF]
, 2001 The tandem mass spectrometry fragments a large number of molecules of the same peptide sequence into charged prefix and suffix subsequences, and then measures mass/charge ratios of these ions.
Chen, Ting +4 more
core +3 more sources
Türk Biyokimya Dergisi, 2023 Owing to its avascular nature, cartilage tissue has a restricted capacity for regeneration. These structural features make it difficult for a fully functional tissue to regenerate after damage.
Yaylacı Seher
doaj +1 more source
Training self-supervised peptide sequence models on artificially chopped proteins [PDF]
arXiv, 2022 Representation learning for proteins has primarily focused on the global understanding of protein sequences regardless of their length. However, shorter proteins (known as peptides) take on distinct structures and functions compared to their longer counterparts. Unfortunately, there are not as many naturally occurring peptides available to be sequenced
arxiv
Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein [PDF]
, 1991 Processing of endogenously synthesized proteins generates short peptides that are presented by MHC class I molecules to CD8 T lymphocytes. Here it is documented that not only the sequence of the presented peptide but also the residues by which it is ...
Braciale +36 more
core +1 more source
Design of embedded-hybrid antimicrobial peptides with enhanced cell selectivity and anti-biofilm activity. [PDF]
PLoS ONE, 2014 Antimicrobial peptides have attracted considerable attention because of their broad-spectrum antimicrobial activity and their low prognostic to induce antibiotic resistance which is the most common source of failure in bacterial infection treatment along
Wei Xu +4 more
doaj +1 more source
Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]
, 2003 A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Basten, E.J.W. +2 more
core +4 more sources
Molecular Plant-Microbe Interactions, 2000 A hexapeptide of amino acid sequence Ac-Arg-Lys-Thr-Trp-Phe-Trp-NH 2 was demonstrated to have antimicrobial activity against selected phytopathogenic fungi that cause postharvest decay in fruits.
Belén López-García +3 more
doaj +1 more source
Mapping the interaction of B cell Leukemia 3 (BCL-3) and nuclear factor κB (NF-κB) p50 identifies a BCL-3-mimetic anti-inflammatory peptide [PDF]
, 2015 The NF-κB transcriptional response is tightly regulated by a number of processes including the phosphorylation, ubiquitination, and subsequent proteasomal degradation of NF-κB subunits.
Carmody, Ruaidhri J. +6 more
core +1 more source
Efficient Prediction of Peptide Self-assembly through Sequential and Graphical Encoding [PDF]
arXiv, 2023 In recent years, there has been an explosion of research on the application of deep learning to the prediction of various peptide properties, due to the significant development and market potential of peptides. Molecular dynamics has enabled the efficient collection of large peptide datasets, providing reliable training data for deep learning. However,
arxiv