Results 41 to 50 of about 1,077,842 (362)
The first salamander defensin antimicrobial peptide. [PDF]
PLoS ONE, 2013 Antimicrobial peptides have been widely identified from amphibian skins except salamanders. A novel antimicrobial peptide (CFBD) was isolated and characterized from skin secretions of the salamander, Cynops fudingensis.
Ping Meng +5 more
doaj +1 more source
A Multi-Modal Contrastive Diffusion Model for Therapeutic Peptide Generation [PDF]
arXiv, 2023 Therapeutic peptides represent a unique class of pharmaceutical agents crucial for the treatment of human diseases. Recently, deep generative models have exhibited remarkable potential for generating therapeutic peptides, but they only utilize sequence or structure information alone, which hinders the performance in generation.
arxiv
Relative affinity constants by electrospray ionization and Fourier transform ion cyclotron resonance mass spectrometry: calmodulin binding to peptide analogs of myosin light chain kinase [PDF]
, 2003 Synthetic RS20 peptide and a set of its point-mutated peptide analogs have been used to analyze the interactions between calmodulin (CaM) and the CaM-binding sequence of smooth-muscle myosin light chain kinase both in the presence and the absence of Ca2+.
Derrick, Peter J. +3 more
core +2 more sources
Sequence-selective Peptide-binding Metallomacrocycles [PDF]
Bulletin of the Korean Chemical Society, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Seung Soo Yoon, Kum Hee Lee
openaire +3 more sources
Jurnal Biodjati, 2017 One of the important enzymes in cellulase complex is β-glucosidase. In this research, adding signal peptide of inulinase gene from Kluyveromyces marxianus, cloning, and expressing of bglp15.2 gene in S. cerevisiae BY4741 had been done.
Armaya Badiatul Fitri +2 more
doaj +1 more source
Denovo-GCN: De Novo Peptide Sequencing by Graph Convolutional Neural Networks
Applied Sciences, 2023 The de novo peptide-sequencing method can be used to directly infer the peptide sequence from a tandem mass spectrum. It has the advantage of not relying on protein databases and plays a key role in the determination of the protein sequences of unknown ...
Ruitao Wu +3 more
doaj +1 more source
Accurate de novo peptide sequencing using fully convolutional neural networks
Nature Communications, 2023 De novo peptide sequencing, which does not rely on a comprehensive target sequence database, provides us with a way to identify novel peptides from tandem mass spectra. However, current de novo sequencing algorithms suffer from low accuracy and coverage,
Kaiyuan Liu +3 more
doaj +1 more source
Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause? [PDF]
, 2006 BACKGROUND: Our aim was to identify the pancreatic cancer diabetogenic peptide. METHODS: Pancreatic tumor samples from patients with (n=15) or without (n=7) diabetes were compared with 6 non-neoplastic pancreas samples using SDS-PAGE.
BALDO G +12 more
core +1 more source
Investigation of a Sequence-Modified Antimicrobial Peptide [PDF]
Biophysical Journal, 2010 Antimicrobial peptides serve as one of the first lines of defense in the immune systems of higher organisms. These peptides specifically target and neutralize infecting bacteria in the host organism while exhibiting little or no toxic effect on host cells.
Luba Arotsky +2 more
openaire +2 more sources
PLoS ONE, 2012 The molecular chaperone GRP78/BiP is a key regulator of protein folding in the endoplasmic reticulum, and it plays a pivotal role in cancer cell survival and chemoresistance.
Danilo Maddalo +11 more
doaj +1 more source