Results 61 to 70 of about 4,535,136 (383)

Extracellular β-Glucosidase Production from bglp15.2 Gene Carrying Inulinase Signal Peptide in Saccharomyces cerevisiae BY4741

open access: yesJurnal Biodjati, 2017
One of the important enzymes in cellulase complex is β-glucosidase. In this research, adding signal peptide of inulinase gene from Kluyveromyces marxianus, cloning, and expressing of bglp15.2 gene in S. cerevisiae BY4741 had been done.
Armaya Badiatul Fitri   +2 more
doaj   +1 more source

Denovo-GCN: De Novo Peptide Sequencing by Graph Convolutional Neural Networks

open access: yesApplied Sciences, 2023
The de novo peptide-sequencing method can be used to directly infer the peptide sequence from a tandem mass spectrum. It has the advantage of not relying on protein databases and plays a key role in the determination of the protein sequences of unknown ...
Ruitao Wu   +3 more
doaj   +1 more source

Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]

open access: yes, 2014
Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
Bailey, Alistair   +3 more
core   +3 more sources

Accurate de novo peptide sequencing using fully convolutional neural networks

open access: yesNature Communications, 2023
De novo peptide sequencing, which does not rely on a comprehensive target sequence database, provides us with a way to identify novel peptides from tandem mass spectra. However, current de novo sequencing algorithms suffer from low accuracy and coverage,
Kaiyuan Liu   +3 more
doaj   +1 more source

APD3: the antimicrobial peptide database as a tool for research and education

open access: yesNucleic Acids Res., 2015
The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3.
Guangshun Wang, Xia Li, Zhe Wang
semanticscholar   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]

open access: yes, 2014
Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna   +56 more
core   +1 more source

A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death.

open access: yesPLoS ONE, 2012
The molecular chaperone GRP78/BiP is a key regulator of protein folding in the endoplasmic reticulum, and it plays a pivotal role in cancer cell survival and chemoresistance.
Danilo Maddalo   +11 more
doaj   +1 more source

Solving peptide sequencing as satisfiability

open access: yesComputers & Mathematics with Applications, 2008
AbstractThis paper presents an approach for determining the amino acid sequence of a peptide through the solution of propositional satisfiability problems. Data obtained from the mass spectrometry analysis of a peptide are used to build a propositional logic formula, whose models represent coherent interpretations of that set of data and can be used to
openaire   +3 more sources

Sequencing of β-Peptides by Mass Spectrometry

open access: yesCHIMIA, 1999
Seven ?-peptides containing up to 18 β2-, β3- and β2,3-amino acids have been subjected to ESI-tandem mass spectrometry (low-energy fragmentation, positive ions). From the fragment ions formed from the free β-peptides, as well as from the corresponding methyl esters (+14 U) and N-acetyl derivatives (+42 U), the known sequences of β-amino acids could be ...
Jürg V. Schreiber   +2 more
openaire   +2 more sources

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