Results 61 to 70 of about 1,077,842 (362)
Journal of Translational Medicine, 2006 Background A number of autoimmune diseases have been clinically and pathologically characterized. In contrast, target antigens have been identified only in a few cases and, in these few cases, the knowledge of the exact epitopic antigenic sequence is ...
Sinha Animesh A +5 more
doaj +1 more source
Structure, Organization, and Expression of the lct Gene for Lacticin 481, a Novel Lantibiotic Produced by Lactococcus lactis [PDF]
, 1993 The structural gene for the lactococcal lantibiotic lacticin 481 (lct) has been identified and cloned using a degenerated 20-mer DNA oligonucleotide based on the amino-terminal 7 amino acid residues of the purified protein.
Desmazeaud, Michel J., +4 more
core +1 more source
Multiple sequence comparison: A peptide matching approach
Theoretical Computer Science, 1995 AbstractWe present in this paper a peptide matching approach to the multiple comparison of a set of protein sequences. This approach consists in looking for all the words that are common to q of these sequences, where q is a parameter.The comparison between words is done by using as reference an object called a model.
Marie-France Sagot +4 more
openaire +7 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]
, 2014 Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna +56 more
core +1 more source
Alignment of nucleotide with peptide sequences
, 1992 ETH, Eidgenössische Technische Hochschule Zürich, Departement Informatik, Institut für Wissenschaftliches Rechnen ...
Knecht, Lukas, Gonnet, Gaston H.
openaire +3 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Jurnal Teknologi dan Industri Pangan, 2018 Bioactive peptides have important roles as functional food ingredients. The sequence patterns of amino acids in a peptide fragment may relate to their functional mechanisms.
Badrut Tamam +4 more
doaj +1 more source
Molecular evolution of a peptide GPCR ligand driven by artificial neural networks. [PDF]
PLoS ONE, 2012 Peptide ligands of G protein-coupled receptors constitute valuable natural lead structures for the development of highly selective drugs and high-affinity tools to probe ligand-receptor interaction.
Sebastian Bandholtz +3 more
doaj +1 more source
Classifying Antimicrobial and Multifunctional Peptides with Bayesian Network Models [PDF]
Peptide Science, Volume 110, Issue 4, 2018, 2018 Bayesian network models are finding success in characterizing enzyme-catalyzed reactions, slow conformational changes, predicting enzyme inhibition, and genomics. In this work, we apply them to statistical modeling of peptides by simultaneously identifying amino acid sequence motifs and using a motif-based model to clarify the role motifs may play in ...
arxiv +1 more source