Results 161 to 170 of about 38,957 (260)

Characterization of Anabaena cyanobacteria : repeated sequences and genes involved in biosynthesis of microcystins and anabaenopeptilides [PDF]

, 2004
Rouhiainen, Leo
core  

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

In Vitro Bioactivity of a Recombinant Human Collagen Peptide in a Filler Biomimetic Skin Model. [PDF]

J Cosmet Dermatol
He C, Wang R, Zhang Q, Wang Y, Huang N.
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols. [PDF]

Biomolecules
Li M, Chen R, Qiao J, Li W, Zhu H.
europepmc   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Controlling Megasynthetase Module-Module Interactions through β-Hairpin Docking Domain Engineering. [PDF]

ACS Chem Biol
Rankin MR, Contreras KL, Gerwick WH, Gerwick L, Smith JL.   +4 more
europepmc   +1 more source

Stimuli‐responsive hydrogels: An intelligent tool for wound management

Interdisciplinary Medicine, EarlyView.
For chronic and complex wounds, this review focuses on intelligent hydrogels capable of responding to wound microenvironmental cues (e.g., pH, enzymes) or external stimuli (e.g., light, electricity). These advanced materials enable the dynamic regulation of drug release and real‐time monitoring of healing progression, thereby offering innovative ...
Debin Zheng, Meiqi Zhu, Xi Liu, Cuiping Zhang, Di Wu, Tianyu Xie, Chen Li, Pei Zhao, Wenting Chen, Xiaobing Fu, Xiaoxue Li   +10 more
wiley   +1 more source

Inhibition mechanism of the fungal β-1,3-glucan synthases by triterpenoid antifungal drugs. [PDF]

Nat Commun
You ZL, Sun L, Wang LX, Ni YR, Lyu RQ, Chen DD, Yun CH, Song T, Song Y, Bai L.   +9 more
europepmc   +1 more source

Discovery of novel conserved peptide domains by ortholog comparison within plant multi-protein families [PDF]

, 2005
Panstruga, R.
core   +1 more source