Results 121 to 130 of about 100,338 (264)

Reprogramming RiPP scaffolds through skeletal editing unlocks chemical space. [PDF]

Chem Sci
Ogawa H, Yu L, Li S, Nagata Y, Chan TK, Matsuda Y, Liu J, Li YX, Nakamura H.   +8 more
europepmc   +1 more source

Self‐Assembled Calcite Architectures for Programmable Information Storage

Advanced Materials Technologies, EarlyView.
Programmable biomineralization enables the formation of 3D calcite architectures that encode information through spatially defined refractive‐index modulations. Data are written via laser‐directed mineralization, stored in stable voxelized mineral structures, and retrieved non‐destructively through optical diffraction, offering a pathway toward ultra ...
Congrui Jin, Yong Huang, Mehdi Ranjkesh Rashteh Roudi   +2 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Chemoselective C-Terminal Activation Platform for Direct Conversion of Native Linear Peptides into Thiazoline/Thiazole Macrocycles. [PDF]

Org Lett
Le BQG, Kwon M, Raj M.
europepmc   +1 more source

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

Advanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

The Biggest Challenge for Prediction of Membrane Permeability of Cyclic Peptides: Scarce Data Availability. [PDF]

J Med Chem
Lamers C.
europepmc   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Identification of Secondary Nucleation Inhibitors of Amyloid-β Aggregation by Cellular Selection of a SICLOPPS Library. [PDF]

Chembiochem
Lee B, Flood B, Potter E, Wang T.
europepmc   +1 more source

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Predicting enzymatic cleavage sites in cyclic peptides with non-canonical amino acids using a Graphormer model trained on MetID user data. [PDF]

Sci Rep
Cifuentes P, Adàlia R, Vasicek LA, Gundersdorf R, Wheeler A, Zamora I.   +5 more
europepmc   +1 more source