Results 271 to 280 of about 203,550 (287)
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Cyclic Peptide Synthesis with Thioacids
Organic Letters, 2010C-Terminal amino acid 9-fluorenylmethylthioesters may be carried through Boc chemistry solution phase peptide synthesis sequences. After insertion of the final residue in the form of an Fmoc carbamate, treatment with piperidine releases a seco-peptide as a C-terminal thioacid that on treatment with Sanger's reagent undergoes cyclization to a cyclic ...
Sasaki, Kaname, Crich, David
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New cyclic peptide proteasome inhibitors
Bioorganic & Medicinal Chemistry Letters, 2009Here we report the study of a new series of vinyl ester cyclopeptide analogues synthesized on the basis of our previous development of a class of cyclopeptides derived from our linear prototype inhibitors. In these compounds, the exocyclic pharmacophoric unit Leu-VE was linked to the gamma-carboxyl group of the glutamic acid residue at the C-terminal ...
BALDISSEROTTO, Anna +3 more
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Synthesis of Cyclic Peptides and Cyclic Proteins via Ligation of Peptide Hydrazides
ChemBioChem, 2012Intramolecular ligation of peptide hydrazides is reported to occur readily, causing the lactamization of fully unprotected peptides in an epimerization-free manner. This method relies on the routine procedures of Fmoc solid-phase peptide synthesis. It can be used to prepare cyclic peptides and cyclic proteins under simpler, mild conditions at lower ...
Ji-Shen, Zheng +4 more
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Cyclic, Modified and Conjugated Peptides
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
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Cyclic peptides. Amino acid-cyclic peptides complexes
Journal of the American Chemical Society, 1974Charles M. Deber, Elkan R. Blout
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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1983
A. Ravi, P. Balaram
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A. Ravi, P. Balaram
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