Results 251 to 260 of about 2,730,255 (384)

Elastomeric peptide

, 2018
It is here claimed an oligopeptide of sequence SJXXZGXP (SEQ ID no. 7), where S is a serine, J is a serine or it is absent, X is independently any desired amino acid, Z is selected from tyrosine, histidine, phenylalanine or tryptophan, G is a glycine and P is a proline, characterized by the fact that at least the residue Z is substituted with at least ...
P. Metrangolo, F. Baldelli, A. Pizzi, M. Linder, M. Pezhman   +4 more
openaire   +2 more sources

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source

Extensive cross-reactive T cell epitopes across SARS-CoV-2 Omicron variant spikes with finite immune evasion mutations. [PDF]

J Transl Med
Gan M, Cao J, Ouyang Q, Xu X, Wang X, Dan P, Yao Y, Fu H, Yao X, Lin X, Lei Q, Fan X.   +11 more
europepmc   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Detection of single-cell enzyme activity by single-time-point stable isotope probing-mass spectrometry. [PDF]

Chem Sci
Wu X, Ma Q, Chen H, Cheng C, Li J, Xu F, Chen Y.   +6 more
europepmc   +1 more source

ChloroP, a neural network‐based method for predicting chloroplast transit peptides and their cleavage sites

Protein Science, 1999
O. Emanuelsson, H. Nielsen, G. Heijne
semanticscholar   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Engineering a Single Amino Acid Bionanozyme for Ultrasensitive Detection of Biomarkers: A WHO‐REASSURE‐ Aligned Approach

Advanced Functional Materials, EarlyView.
A unique 2D bionanozyme, engineered from a single amino acid and copper ions, demonstrates peroxidase‐mimicking catalytic activity. This efficient and simple bionanozyme allows for ultrasensitive, equipment‐free visual detection of key biomarkers in both test and real samples, meeting the WHO‐REASSURE standards for practical diagnostic applications ...
Subrat Vishwakarma, Om Shanker Tiwari, Vijay Kumar Patel, Ruchi Shukla, Ehud Gazit, Pandeeswar Makam   +5 more
wiley   +1 more source

A comparative study of computational modeling approaches for evaluating structural dynamics and algorithmic suitability of short length peptides. [PDF]

Sci Rep
Anand AA, Anwar S, Yadav V, Samanta SK.
europepmc   +1 more source

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

Nature, 1991
K. Falk, O. Rötzschke, Stefan Stevanovié, G. Jung, H. Rammensee   +4 more
semanticscholar   +1 more source