Results 21 to 30 of about 2,703,759 (384)

A new family of diverse skin peptides from the microhylid frog genus phrynomantis [PDF]

open access: yes, 2020
A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the Microhylidae, have ...
Ballet, Steven   +7 more
core   +1 more source

Fabrication of fluorescent nanospheres by heating PEGylated tetratyrosine nanofibers

open access: yesScientific Reports, 2021
Aromatic polypeptides have recently drawn the interest of the research community for their capability to self-assemble into a variety of functional nanostructures.
Enrico Gallo   +8 more
doaj   +1 more source

Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides [PDF]

open access: yes, 2018
A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Gannon, Susan   +7 more
core   +1 more source

Antimicrobial peptides: Application informed by evolution

open access: yesScience, 2020
Small-molecule defense Small-peptide defense molecules are produced by most organisms to fend off invasion by bacteria. The antimicrobial peptides that we know about so far show substantial diversity, synergism, and alternative functions.
B. Lazzaro, M. Zasloff, J. Rolff
semanticscholar   +1 more source

Peptides, Antibodies, Peptide Antibodies and More [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire   +5 more sources

Analysis of iodinated quorum sensing peptides by LC-UV/ESI ion trap mass spectrometry [PDF]

open access: yes, 2018
Five different quorum sensing peptides (QSP) were iodinated using different iodination techniques. These iodinated peptides were analyzed using a C-18 reversed phase HPLC system, applying a linear gradient of water and acetonitrile containing 0.1% (m/v ...
De Spiegeleer, Bart   +5 more
core   +2 more sources

Peptide Stapling Applied to Antimicrobial Peptides

open access: yesAntibiotics, 2023
Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço   +4 more
openaire   +3 more sources

Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P®)

open access: yesMolecules, 2023
The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomimetic ...
Alexia Mattellone   +7 more
doaj   +1 more source

Development and Challenges of Antimicrobial Peptides for Therapeutic Applications

open access: yesAntibiotics, 2020
More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have been approved by the U.S. Food and Drug Administration (FDA). Now commercialized, these seven peptides have mostly been utilized for topical medications, though some ...
Charles H. Chen, T. Lu
semanticscholar   +1 more source

Characterization of a novel lipase from Pseudomonas aeruginosa

open access: yesNova Biotechnologica et Chimica, 2019
Lipases cleaving oils into fatty acids and glycerol are of great interest for the use in increasing the efficiency of fuels. In this work, a novel lipase from Pseudomonas aeruginosa, P.
Berdiev Nodir Sh.   +4 more
doaj   +1 more source

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