Results 31 to 40 of about 1,099,232 (317)

Microvascular Metrics on Diabetic Retinopathy Severity: Analysis of Diabetic Eye Images from Real-World Data

Biomedicines
Objective: To quantify microvascular lesions in a large real-world data (RWD) set, based on single central retinal fundus images of diabetic eyes from different origins, with the aim of validating its use as a precision tool for classifying diabetic ...
Cristina Cuscó, Pau Esteve-Bricullé, Ana Almazán-Moga, Jimena Fernández-Carneado, Berta Ponsati   +4 more
doaj   +1 more source

Role of biological rhythms in the performance of physical activity

Journal of Physical Fitness and Sports Medicine, 2017
Most organisms display various periodicities. Periodicity has been observed in humans in association with sleep, body temperature and hormone secretion. The molecular mechanisms involved are being elucidated by the investigation of clock genes in mammals.
Takahiro Sato, Takanori Ida, Masayasu Kojima   +2 more
doaj   +1 more source

Stable Formulations of Peptide-Based Nanogels

Molecules, 2020
Recently, nanogels have been identified as innovative formulations for enlarging the application of hydrogels (HGs) in the area of drug delivery or in diagnostic imaging.
Elisabetta Rosa, Carlo Diaferia, Enrico Gallo, Giancarlo Morelli, Antonella Accardo   +4 more
doaj   +1 more source

Solid-state optical properties of self-assembling amyloid-like peptides with different charged states at the terminal ends

Scientific Reports, 2022
The self-assembling of small peptides not only leads to the formation of intriguing nanoarchitectures, but also generates materials with unexpected functional properties.
Chiara Schiattarella, Carlo Diaferia, Enrico Gallo, Bartolomeo Della Ventura, Giancarlo Morelli, Luigi Vitagliano, Raffaele Velotta, Antonella Accardo   +7 more
doaj   +1 more source

Acyl modifications in bovine, porcine, and equine ghrelins

Frontiers in Endocrinology
Ghrelin is a peptide hormone with various important physiological functions. The unique feature of ghrelin is its serine 3 acyl-modification, which is essential for ghrelin activity.
Takanori Ida, Hatsumi Tominaga, Eri Iwamoto, Akito Kurogi, Ayaka Okura, Kengo Shimada, Johji Kato, Atsutoshi Kuwano, Hirotaka Ode, Sayaka Nagata, Kazuo Kitamura, Takashi Yazawa, Miho Sato-Hashimoto, Masahiro Yasuda, Mikiya Miyazato, Yuki Shiimura, Takahiro Sato, Masayasu Kojima   +17 more
doaj   +1 more source

Protection effects of rice protein hydrolysate on UVB-irradiated photodamage in Hartley guinea pigs skin and human skin fibroblasts

Journal of Functional Foods, 2021
This study examined the ameliorative effects of rice protein hydrolysate (RPH) on UVB irradiation-induced photodamage in Hartley guinea pigs, particularly its influence on antioxidant indicators, moisture content, hydroxyproline (HYP) content and skin ...
Ruixue Zhang, Ying Wei, Jiangtao Zhang, Muyi Cai, Lu Lu, Lei Fang, Xiuyuan Qin, Ruizeng Gu   +7 more
doaj  

Development and Validation of a Prediction Model for Cardiovascular Events in Exercise Assessment of Coronary Heart Disease Patients After Percutaneous Coronary Intervention

Frontiers in Cardiovascular Medicine, 2022
ObjectiveThis study aimed to develop a model for predicting cardiovascular events in the exercise assessment of patients with coronary heart disease after percutaneous coronary intervention (PCI) based on multidimensional clinical information.MethodsA ...
Tao Shen, Chuan Ren, Wei Zhao, Wei Zhao, Liyuan Tao, Shunlin Xu, Chengduo Zhang, Wei Gao   +7 more
doaj   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

A peptide puzzle

eLife, 2018
Why does cancer develop in situations where the immune system is perfectly capable of eliminating it?
Jian Guan, Nilabh Shastri
openaire   +4 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source