Results 31 to 40 of about 2,534,576 (425)
Trans-Bilayer Ion Conduction by Proline Containing Cyclic Hexapeptides and Effects of Amino Acid Substitutions on Ion Conducting Properties [PDF]
, 2010 Several ion channel forming cyclic peptides have been reported over the past two decades and various ion conducting mechanisms have been proposed. In this article, we report on amino acid substitutions in cyclic hexapeptides and their effects on the ion ...
Aoyagi, Haruhiko +6 more
core +2 more sources
Antibiotics, 2020 As natural host defense compounds produced by numerous prokaryotic and eukaryotic life forms, antimicrobial peptides (AMPs) are now emerging as solid candidate chemotherapeutic drugs to fight against the various types of pathogenic Gram-positive and Gram-negative bacteria, especially those resistant to current antibiotics [...]
openaire +5 more sources
Toxins, 2019 Prokineticins are highly conserved small peptides family expressed in all vertebrates, which contain a wide spectrum of functions. In this study, a prokineticin homolog (Bv8-AJ) isolated from the venom of frog Amolops jingdongensis was fully ...
Jiajia Chang +6 more
doaj +1 more source
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.
Proceedings of the National Academy of Sciences of the United States of America, 1998 We describe a hypothalamus-specific mRNA that encodes preprohypocretin, the putative precursor of a pair of peptides that share substantial amino acid identities with the gut hormone secretin.
L. Lecea +14 more
semanticscholar +1 more source
Pharmaceuticals, 2022 SOCS3 (suppressor of cytokine signaling 3) protein suppresses cytokine-induced inflammation and its deletion in neurons or immune cells increases the pathological growth of blood vessels. Recently, we designed several SOCS3 peptidomimetics by assuming as
Sara La Manna +4 more
doaj +1 more source
In silico structural evaluation of short cationic antimicrobial peptides [PDF]
, 2018 © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Cationic peptides with ...
Malkinson, John +3 more
core +2 more sources
A New Era of Antibiotics: The Clinical Potential of Antimicrobial Peptides
International Journal of Molecular Sciences, 2020 Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health. The traditional antibiotic pipeline has been exhausted, prompting research into alternate antimicrobial strategies.
K. Browne +6 more
semanticscholar +1 more source
Training self-supervised peptide sequence models on artificially chopped proteins [PDF]
arXiv, 2022 Representation learning for proteins has primarily focused on the global understanding of protein sequences regardless of their length. However, shorter proteins (known as peptides) take on distinct structures and functions compared to their longer counterparts. Unfortunately, there are not as many naturally occurring peptides available to be sequenced
arxiv
Immunotherapy with peptides [PDF]
Allergy, 2011 Specific allergen immunotherapy is clinically effective and disease modifying. It has a duration of effect that exceeds the treatment period and prevents both the progression of allergic rhinitis to asthma and the acquisition of new allergic sensitizations.
Daniel M. Moldaver, Mark Larché
openaire +3 more sources
Viruses, 2018 Actinobacteria are a phylum of bacteria known for their potential in producing structurally diversified natural products that are always associated with a broad range of biological activities.
Fangfang Li +8 more
doaj +1 more source