Results 111 to 120 of about 121,463 (292)

Progress in the detection of gut microbiota based on microfluidic technology

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Gut microbiota, a complex microbial community in the human intestine, are vital for digestion, nutrient absorption, and immune regulation, maintaining gut micro‐ecological balance. Accurate detection of its composition, structure, and function is crucial for understanding the relationship between health and disease, early disease diagnosis ...
Yuan Tan   +3 more
wiley   +1 more source

Translation of peptidoglycan metabolites into immunotherapeutics

open access: yesClinical & Translational Immunology, 2019
The discovery of defined peptidoglycan metabolites that activate host immunity and their specific receptors has revealed fundamental insights into host–microbe recognition and afforded new opportunities for therapeutic development against infection and ...
Matthew E Griffin   +3 more
doaj   +1 more source

Dynamics of the peptidoglycan biosynthetic machinery in the stalked budding bacterium Hyphomonas neptunium [PDF]

open access: bronze, 2016
Emöke Cserti   +9 more
openalex   +1 more source

Achieving superior therapeutic effects on methicillin‐resistant Staphylococcus aureus infection via simple sulfonation process for preparing zwitterionic photosensitizer

open access: yesInterdisciplinary Medicine, EarlyView.
The sulfonated zwitterionic photosensitizer (PYSO3) is synthesized by reacting maleic anhydride derivatives with 4‐aminopyridine to form PY, followed by sulfonation with 1,4‐butane sultone. It exhibits both photothermal and photodynamic properties, enabling effective eradication of MRSA and biofilms, as well as promoting wound healing in mice ...
Changxu Zhu   +10 more
wiley   +1 more source

The hidden base of the iceberg: gut peptidoglycome dynamics is foundational to its influence on the host

open access: yesGut Microbes
The intestinal microbiota of humans includes a highly diverse range of bacterial species. All these bacteria possess a cell wall, composed primarily of the macromolecule peptidoglycan.
Richard Wheeler, Ivo Gomperts Boneca
doaj   +1 more source

Effect of Nanoparticles Type and Content on the Antimicrobial Activity of Magnetoelectric Polymer‐Based Composites

open access: yesMacromolecular Bioscience, EarlyView.
Magnetoelectric P(VDF‐TrFE) nanocomposites containing CFO or Fe3O4 nanoparticles were developed to generate electroactive microenvironments under magnetic stimulation. At 1 Hz, particularly with 20% CFO, strong antimicrobial effects were observed against E. coli and S. aureus. This approach highlights the potential of magnetically activated surfaces to
Joana Moreira   +6 more
wiley   +1 more source

Sulfonium‐Based Antimicrobial Block Copolymers: Influence of Hydrophobicity on Biological Activity and Antibiotic Synergy

open access: yesMacromolecular Rapid Communications, EarlyView.
Sulfonium‐based antimicrobial block copolymers combine an active cationic hydrophobic block with a neutral hydrophilic block to improve cytocompatibility. The hydrophobicity of the sulfonium‐based block controls the activity against S. aureus and E coli.
Sidra Kanwal   +5 more
wiley   +1 more source

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

open access: yesMacromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh   +2 more
wiley   +1 more source

Artichoke Bracts and Stems Residues as Active Filler for Poly(Butylene Succinate‐Co‐Adipate) (PBSA) Composites: From Agro‐Waste to a New Sustainable Material

open access: yesPolymer Composites, EarlyView.
PBSA‐based biocomposites made from artichoke bract and stem powders have been characterised and formulated for agricultural and food applications, such as active mulching films. ABSTRACT In the context of a growing bioeconomy and the drive for sustainable materials, new biocomposites were formulated by incorporating poly(butylene succinate‐co‐adipate) (
Carmen Minichiello   +8 more
wiley   +1 more source

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