Results 121 to 130 of about 118,125 (294)

Glucose‐Responsive and Analgesic Gel for Diabetic Subcutaneous Abscess Treatment by Simultaneously Boosting Photodynamic Therapy and Relieving Hypoxia

open access: yesAdvanced Science, EarlyView.
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang   +12 more
wiley   +1 more source

Zymogram Assay for the Detection of Peptidoglycan Hydrolases in Streptococcus mutans

open access: yesBio-Protocol, 2013
Peptidoglycan hydrolases or autolysins are enzymes capable of cleaving covalent bonds in bacterial peptidoglycan cell wall layer. They can participate in the cell division process, in the release of turnover products from peptidoglycan during cell growth,
Delphine Dufour, Céline Lévesque
doaj   +1 more source

Obtaining and Characteristic of the Autolysate of Lactic Acid Bacteria [PDF]

open access: yes, 2018
Fragments of bacterial peptidoglycan relating to compounds of the muropeptide series have high biological activity. They have an immunological effect, due to the fact that they are signals for immune receptors and, accordingly, their activators. In order
Cherno, N. (Natalia)   +1 more
core   +2 more sources

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

Model of pathogenesis of psoriasis. Part 1. Systemic psoriatic process [PDF]

open access: yesarXiv, 2011
Analytical study of results of experimental and theoretical works on pathogenesis of psoriatic disease was conducted. Psoriasis is dermal implication of systemic psoriatic process (SPP). New SPP model explaining results of clinical and laboratory experiments was formulated.
arxiv  

Structures of Sortase B from Staphylococcus aureus and Bacillus anthracis Reveal Catalytic Amino Acid Triad in the Active Site [PDF]

open access: yes, 2004
Surface proteins attached by sortases to the cell wall envelope of bacterial pathogens play important roles during infection. Sorting and attachment of these proteins is directed by C-terminal signals. Sortase B of S.
Gornicki, Piotr   +7 more
core   +1 more source

High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

open access: yesAdvanced Science, EarlyView.
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti   +3 more
wiley   +1 more source

Native cellular architecture of Treponema denticola revealed by cryo-electron tomography [PDF]

open access: yes, 2009
Using cryo-electron tomography, we are developing a refined description of native cellular structures in the pathogenic spirochete Treponema denticola. Tightly organized bundles of periplasmic flagella were readily observed in intact plunge-frozen cells.
Hsieh, Chyong-Ere   +4 more
core   +1 more source

In Situ Electrically Resettable Field‐Effect Transistor Biosensors for Continuous and Multiplexed Neurotransmitter Detection

open access: yesAdvanced Science, EarlyView.
The research team integrated a potentiometrically controlled pH electrode with carbon nanotube (CNT) field‐effect transistor (FET) biosensors on a single chip using compatible processes. By employing zonal modification and optimized pH‐sensitive probes, they achieved simultaneous quadruple‐target detection and tenfold reusability under physiological ...
Bo Xiao   +6 more
wiley   +1 more source

Comparative Analysis of Peptidoglycans From Pseudomonas aeruginosa Isolates Recovered From Chronic and Acute Infections

open access: yesFrontiers in Microbiology, 2019
Pseudomonas aeruginosa is one of the first causes of acute nosocomial and chronic infections in patients with underlying respiratory pathologies such as cystic fibrosis (CF). It has been proposed that P.
Gabriel Torrens   +8 more
doaj   +1 more source

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