Results 61 to 70 of about 147,833 (381)
PLoS Pathogens, 2022 Salmonella enterica causes intracellular infections that can be limited to the intestine or spread to deeper tissues. In most cases, intracellular bacteria show moderate growth.
Sara B Hernández +10 more
doaj +1 more source
Membrane-partitioned cell wall synthesis in mycobacteria
eLife, 2021 Many antibiotics target the assembly of cell wall peptidoglycan, an essential, heteropolymeric mesh that encases most bacteria. In rod-shaped bacteria, cell wall elongation is spatially precise yet relies on limited pools of lipid-linked precursors that ...
Alam García-Heredia +8 more
doaj +1 more source
Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2*
Journal of Biological Chemistry, 1999 The life-threatening complications of sepsis in humans are elicited by infection with Gram-negative as well as Gram-positive bacteria. Recently, lipopolysaccharide (LPS), a major biologically active agent of Gram-negative bacteria, was shown to mediate ...
R. Schwandner +4 more
semanticscholar +1 more source
mBio, 2015 Most bacterial cells are enclosed in a single macromolecule of the cell wall polymer, peptidoglycan, which is required for shape determination and maintenance of viability, while peptidoglycan biosynthesis is an important antibiotic target.
Richard Wheeler +9 more
doaj +1 more source
Scientific Reports, 2020 The peptidoglycan layer is responsible for maintaining bacterial cell shape and permitting cell division. Cell wall growth is facilitated by peptidoglycan synthases and hydrolases and is potentially modulated by components of the central carbon ...
Jad Sassine +4 more
doaj +1 more source
A lysozyme-like protein in Brucella abortus is involved in the early stages of intracellular replication [PDF]
, 2013 Secretion of proteins in Gram-negative bacteria is a high-energy consuming process that requires the translocation across two membranes and a periplasmic space composed of a mesh like layer, the peptidoglycan.
Czibener, Cecilia +2 more
core +1 more source
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogen
FEMS Microbiology Reviews, 2019 Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis, remains one of the leading causes of mortality across the world. There is an urgent requirement to build a robust arsenal of effective antimicrobials, targeting novel ...
Arundhati Maitra +6 more
semanticscholar +1 more source
Resistance of O-acetylated gonococcal peptidoglycan to human peptidoglycan-degrading enzymes [PDF]
Infection and Immunity, 1983 Two naturally occurring forms of gonococcal peptidoglycan (PG) were tested for their susceptibility to human PG hydrolases. Purified 3H-labeled PG substituted extensively with O-acetyl derivatives (O-PG; from Neisseria gonorrhoeae FA19) and 14C-labeled O-acetyl-deficient PG (non-O-PG; from N. gonorrhoeae RD5) were mixed together and treated with either
S C Swim +3 more
openaire +3 more sources
Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in North America. If early infection is untreated, it can result in late-stage manifestations, including arthritis. Although antibiotics are
B. Jutras +12 more
semanticscholar +1 more source
Uptake, recognition and responses to peptidoglycan in the mammalian host
FEMS Microbiology Reviews, 2020 Microbiota, and the plethora of signalling molecules that they generate, are a major driving force that underlies a striking range of inter-individual physioanatomic and behavioural consequences for the host organism.
P. Bastos, R. Wheeler, I. Boneca
semanticscholar +1 more source