Results 51 to 60 of about 101,965 (169)

Simulated Trampling Disturbance Alters Biocrust Microbial Communities and Soil Functions: A Container‐Based Mesocosm Experiment

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Biological soil crusts (biocrusts) are crucial components of dryland ecosystems; however, they are highly vulnerable to anthropogenic disturbances, particularly trampling caused by grazing. To evaluate the impacts of trampling on biocrust structure, microbial communities, and soil functions, we conducted a mesocosm‐based simulated disturbance ...
Lu Chen   +6 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi   +4 more
wiley   +1 more source

Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance

open access: yesMedicine Advances, EarlyView.
This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani   +5 more
wiley   +1 more source

Structural and Biochemical Characterization of the Diaminopimelate Epimerase DapF From Pseudomonas aeruginosa PA14

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The emergence of antibiotic resistance in bacteria is a major threat to global public health. To combat increasingly drug‐resistant bacteria like Pseudomonas aeruginosa, new targets for pharmaceuticals need to be explored. One such potential target for P.
Philipp Schneider   +4 more
wiley   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

open access: yesResponsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan   +8 more
wiley   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

open access: yesSmall, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale   +10 more
wiley   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

open access: yesSmall, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li   +3 more
wiley   +1 more source

Non‐Perturbative Bacterial Identification Directly From Solid Agar Plates Using Raman Micro‐Spectroscopy and Machine Learning

open access: yesSmall Methods, EarlyView.
This work demonstrates a simple, rapid bacterial identification directly from unopened solid agar culture that neither perturbs culture conditions nor requires extrinsic labels, promising seamless integration of Raman spectroscopy into clinical and microbiology laboratory workflows.
Jeong Hee Kim   +3 more
wiley   +1 more source

Liquid Phase Backscattered Scanning Electron Microscopy of Bacillus subtilis Spores

open access: yesSmall Methods, EarlyView.
Graphene encapsulation enables liquid‐phase BSE‐SEM to visualize subsurface architecture of whole, hydrated Bacillus subtilis spores without staining. This approach is applied to visualize dormant spores and subsequent structural changes during spore germination, while imaging across a range of beam energies and Monte Carlo simulations provide a ...
Jack Bromley   +8 more
wiley   +1 more source

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