Results 61 to 70 of about 155,443 (280)

Peptidoglycan editing in non-proliferating intracellular Salmonella as source of interference with immune signaling.

PLoS Pathogens, 2022
Salmonella enterica causes intracellular infections that can be limited to the intestine or spread to deeper tissues. In most cases, intracellular bacteria show moderate growth.
Sara B Hernández, Sónia Castanheira, M Graciela Pucciarelli, Juan J Cestero, Gadea Rico-Pérez, Alberto Paradela, Juan A Ayala, Sonsoles Velázquez, Ana San-Félix, Felipe Cava, Francisco García-Del Portillo   +10 more
doaj   +1 more source

Native cellular architecture of Treponema denticola revealed by cryo-electron tomography [PDF]

, 2009
Using cryo-electron tomography, we are developing a refined description of native cellular structures in the pathogenic spirochete Treponema denticola. Tightly organized bundles of periplasmic flagella were readily observed in intact plunge-frozen cells.
Hsieh, Chyong-Ere, Izard, Jacques, Limberger, Ronald J., Mannella, Carmen A., Marko, Michael   +4 more
core   +1 more source

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves, Drulis-Kawa, Zuzanna, Maciejewska, Barbara, Majkowska-Skrobek, Grazyna, Łątka, Agnieszka   +4 more
core   +1 more source

Peptidoglycan in obligate intracellular bacteria [PDF]

Molecular Microbiology, 2017
SummaryPeptidoglycan is the predominant stress‐bearing structure in the cell envelope of most bacteria, and also a potent stimulator of the eukaryotic immune system. Obligate intracellular bacteria replicate exclusively within the interior of living cells, an osmotically protected niche. Under these conditions peptidoglycan is not necessarily needed to
Christian Otten, Matteo Brilli, Waldemar Vollmer, Patrick H. Viollier, Jeanne Salje   +4 more
openaire   +5 more sources

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Towards an Ontological Representation of Resistance: The Case of MRSa [PDF]

, 2009
This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. Resistance terms from various existing ontologies are examined and found to be either overly narrow, inconsistent ...
Albert Goldfain, Barry Smith, Lindsay G. Cowell   +2 more
core   +3 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK–TssFG subcomplex [PDF]

, 2014
Gram-negative bacteria use the Type VI secretion system (T6SS) to inject toxic proteins into rival bacteria or eukaryotic cells. However, the mechanism of the T6SS is incompletely understood. In the present study, we investigated a conserved component of
Alan R. Prescott, Aschtgen, Aschtgen, Aschtgen, Aschtgen, Ballister, Basler, Basler, Bonemann, Bonemann, Boyer, Burtnick, Casabona, Casabona, Cascales, Coulthurst, Dong, English, Felisberto-Rodrigues, Francesca R. Cianfanelli, Fritsch, Gerlach, Grant English, Holland, Hood, Jack, Kaniga, Kapitein, Kapitein, Laue, Leiman, Leiman, Lossi, Ma, Ma, Ma, MacIntyre, Mougous, Murdoch, Olwyn Byron, Pell, Potvin, Pukatzki, Rao, Rickman, Russell, Russell, Sambrook, Sarah J. Coulthurst, Schell, Schuck, Schwarz, Shneider, Silverman, Srikannathasan, Suarez, Vistica, Whitney, Zheng, Zheng, Zoued   +60 more
core   +3 more sources

Resistance of O-acetylated gonococcal peptidoglycan to human peptidoglycan-degrading enzymes [PDF]

Infection and Immunity, 1983
Two naturally occurring forms of gonococcal peptidoglycan (PG) were tested for their susceptibility to human PG hydrolases. Purified 3H-labeled PG substituted extensively with O-acetyl derivatives (O-PG; from Neisseria gonorrhoeae FA19) and 14C-labeled O-acetyl-deficient PG (non-O-PG; from N. gonorrhoeae RD5) were mixed together and treated with either
R S, Rosenthal, W J, Folkening, D R, Miller, S C, Swim   +3 more
openaire   +2 more sources

Efficient Self‐Cleaning and Anti‐Bacterial Behavior Realized by Hierarchical Structure in Hybrid Waterborne Polyurethane Coatings Containing Photocatalyst

Advanced Materials Interfaces, EarlyView.
Hybrid WPU coatings with a hierarchical structure are constructed by first directional freezing polymerization of degradable hydrogels with a vertical channel structure and then filling these channels with aqueous WPU solution containing carbon nitride (g‐C3N4) nanosheets.
Xiaobei Zhou, Jing Xu, Jie Yu, Jie Liu, Meiqun Hu, Lie Zhao, Peter Müller‐Buschbaum, Dongming Qi, Qi Zhong   +8 more
wiley   +1 more source