Results 41 to 50 of about 11,815 (217)

The Effect of NAG–thiazoline on Morphology and Surface Hydrophobicity of Escherichia Coli [PDF]

, 2004
The β-hexosaminidase inhibitor and structural analog of the putative oxazolium reaction intermediate of lytic transglycosylases, N-acetylglucosamine thiazoline (NAG–thiazoline), was synthesized in 46% overall yield and tested as an inhibitor of ...
Blackburn, Neil T., Clarke, Anthony J., Reid, Christopher W.   +2 more
core   +2 more sources

Characterisation of the peptidoglycan hydrolases of Listeria monocytogenes EGD [PDF]

FEMS Microbiology Letters, 2006
The peptidoglycan hydrolase profile of Listeria monocytogenes EGD has been characterised under a variety of environmental and physiological conditions, using renaturing sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The profiles show activities ranging from 29 to 186 kDa.
Simon J. Foster, Anna M. McLaughlan
openaire   +3 more sources

Peptidoglycan Hydrolase Fusions Maintain Their Parental Specificities [PDF]

Applied and Environmental Microbiology, 2006
ABSTRACT The increased incidence of bacterial antibiotic resistance has led to a renewed search for novel antimicrobials. Avoiding the use of broad-range antimicrobials through the use of specific peptidoglycan hydrolases (endolysins) might reduce the incidence of antibiotic-resistant pathogens worldwide ...
David M. Donovan, Shengli Dong, Wes Garrett, Geneviève M. Rousseau, Sylvain Moineau, David G. Pritchard   +5 more
openalex   +4 more sources

Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile

Microbial Cell, 2018
Clostridium difficile, also known as Clostriodioides difficile, is a Gram positive, spore-forming bacterium and a leading cause of antibiotic-associated diarrhea in nosocomial environments. The key virulence factors of this pathogen are two toxins, toxin
Imane El Meouche, Johann Peltier
doaj   +1 more source

The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes [PDF]

, 2005
Resuscitation-promoting factor (RPF) proteins reactivate stationary-phase cultures of (G+C)-rich Gram-positive bacteria including the causative agent of tuberculosis, Mycobacterium tuberculosis.
AT Brunger, BA Johnson, Brian Henderson, Christian Roumestand, Claire Bagnéris, D Sharma, EJ van Asselt, EJ van Asselt, G Cornilescu, GV Mukamolova, GV Mukamolova, GV Mukamolova, H Song, JB Raymond, JG Lees, JL Pons, JM Tufariello, John Ward, JP Linge, L Holm, M Cohen-Gonsaud, M Cohen-Gonsaud, M Hartmann, Martin Cohen-Gonsaud, Nicholas H Keep, Philippe Barthe, R Koradi, RA Laskowski   +27 more
core   +2 more sources

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves, Drulis-Kawa, Zuzanna, Maciejewska, Barbara, Majkowska-Skrobek, Grazyna, Łątka, Agnieszka   +4 more
core   +1 more source

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation [PDF]

, 2020
The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and ...
A Ghafoor, A Morin, AB Boraston, AW Blake, C Bundalovic-Torma, C Guerrero, C Ryder, C Steentoft, C Vuong, CM Payne, Collaborative Computational Project Number 4., CS Cummins, DC Sheppard, DE Blair, DE Blair, DJ Little, DJ Little, DJ Little, E Andrés, E Potterton, EN Kitova, F Le Mauff, F Sievers, FN Gravelat, FN Gravelat, GB Whitfield, GD Brown, GM Sheldrick, GM Sheldrick, H Aragunde, H Ashkenazy, H Ostapska, H Takada, H Zakariassen, J Hoßbach, J Sun, JA Jorge, JA Jorge, JJ Distler, JJ Tesmer, JL Reissig, JW Jensen, K Miyazawa, K Mizutani, KM Colvin, LA Kelley, LK Jennings, LS Marmont, M Gonzalez, M Oda, M Strong, MD Winn, MJ Lee, MJ Lee, MM Shaik, N Nwe, NA Baker, NC Bamford, NC Bamford, P Emsley, P Ruperez, P Vasseur, PC Bardalaye, PD Adams, PD Adams, RC Edgar, RE Lewis, S Jana, S Kaur, S Kumar, SC Potter, SF Altschul, T Fontaine, T Inoue, V Pokrovskaya, VE Fadouloglou, VK Köseoğlu, W Vollmer, W Wang, X Wang, X-L Li, Y Araki, Y Itoh, Y Kidani, Y Kidani   +84 more
core   +3 more sources

A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria [PDF]

, 2020
Predator-prey interactions play important roles in the cycling of marine organic matter. Here we show that a Gram-negative bacterium isolated from marine sediments (Pseudoalteromonas sp.
Chen, Xiu-Lan, Chen, Yin, Ding, Haitao, Li, Chun-Yang, Lidbury, Ian, McMinn, Andrew, Su, Hai-Nan, Tang, Bai-Lu, Wang, Lei, Wang, Min, Wang, Peng, Yang, Jie, Yu, Yang, Zhang, Xi-Ying, Zhang, Yu-Zhong, Zhao, Hui-Lin, Zhong, Shuai   +16 more
core   +2 more sources

Bacterial growth does require peptidoglycan hydrolases [PDF]

Molecular Microbiology, 2012
SummaryMost bacteria surround their cytoplasmic membrane with a net‐like, elastic heteropolymer, the peptidoglycan sacculus, to protect themselves from bursting due to the turgor and to maintain cell shape. It has been assumed that growing bacteria require peptidoglycan hydrolases to open meshes in the peptidoglycan net allowing the insertion of the ...
openaire   +3 more sources

Cell morphology maintenance in Bacillus subtilis through balanced peptidoglycan synthesis and hydrolysis

Scientific Reports, 2020
The peptidoglycan layer is responsible for maintaining bacterial cell shape and permitting cell division. Cell wall growth is facilitated by peptidoglycan synthases and hydrolases and is potentially modulated by components of the central carbon ...
Jad Sassine, Joana Sousa, Michael Lalk, Richard A. Daniel, Waldemar Vollmer   +4 more
doaj   +1 more source