Results 1 to 10 of about 4,910 (132)

Association between the polymorphisms of angiotensin converting enzyme (Peptidyl-Dipeptidase A) INDEL mutation (I/D) and Angiotensin II type I receptor (A1166C) and breast cancer among post menopausal Egyptian females [PDF]

Alexandria Journal of Medicine, 2014
Renin angiotensin system (RAS) is involved in the regulation of cardiovascular homeostasis. Angiotensin (Ang II) is converted from angiotensin I via angiotensin converting enzyme (ACE). Ang II exerts its effects by binding to two types of receptors; AT1R
Rania Mohamed El Sharkawy, Ahmed Mohamed Zaki, Amal Abd El Fattah Kamel, Rania Nabil Bedair, Ahmed Saad Ahmed   +4 more
doaj   +2 more sources

Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor. [PDF]

FEBS J, 2016
Masuyer G, Cozier GE, Kramer GJ, Bachmann BO, Acharya KR.   +4 more
europepmc   +3 more sources

Levels of angiotensin-converting enzyme 1 and 2 in serum and urine of children with Sickle Cell Disease

Brazilian Journal of Nephrology, 2021
Introduction: Sickle cell nephropathy begins in childhood and presents early increases in glomerular filtration, which, over the long term, can lead to chronic renal failure.
Ho Chi Hsien, Dulce Elena Casarini, João Tomas de Abreu Carvalhaes, Fernanda Aparecida Ronchi, Lilian Caroline Gonçalves de Oliveira, Josefina Aparecida Pellegrini Braga   +5 more
doaj   +2 more sources

Aristolochic acid induces chronic kidney disease in ace knockout mice

International Journal of Preventive Medicine, 2021
Background: Aristolochic acid I (AAI) is an extract from Chinese herbs that causes progressive interstitial nephritis. The aim of this research is to know whether chymases play the crucial role in AAI-induced nephropathy.
Jia-Ping Wu
doaj   +1 more source

Research progress on the relationship between ACE2 ⁃ Ang ⁃ (1 ⁃ 7) ⁃ MasR axis and central nervous system diseases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Renin⁃angiotensin system (RAS) plays an important role in maintaining cardiovascular homeostasis, water and electrolyte balance in the body, and angiotensin converting enzyme Ⅱ (ACE2) and its axis of action angiotensin⁃(1⁃7) [Ang⁃(1⁃7)] and Mas receptor (
LIANG He , LIN Jian⁃wen , MO Ming, XIE Lu⁃shuang , DU Shi⁃wei , LIU Yi   +5 more
doaj   +1 more source

Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia

Journal of Extracellular Vesicles, Volume 12, Issue 12, December 2023., 2023
Abstract Periodontitis is a chronic inflammatory disease caused by periodontal pathogens in subgingival plaque and is associated with systemic inflammatory diseases. Extracellular vesicles (EVs) released from host cells and pathogens carry a variety of biological molecules and are of interest for their role in disease progression and as diagnostic ...
Younggap Lim, Hyun Young Kim, Dohyun Han, Bong‐Kyu Choi   +3 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets

British Journal of Pharmacology, Volume 180, Issue S2, Page S1-S22, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, O. Peter Buneman, Elena Faccenda, Simon D. Harding, Michael Spedding, John A. Cidlowski, Doriano Fabbro, Anthony P. Davenport, Jörg Striessnig, Jamie A. Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi P. Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill Martemyanov, Luke D. Mascarenhas, Harrison McNabb, Carolina Montañez‐Miranda, Osita Ogujiofor, Hoa Phan, David L. Roman, Vincent Shaw, Benita Sjogren, Christopher Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie Sutton, Menbere Wendimu, Thomas Wilkie, Keqiang Xie, Qian Zhang, Yalda Zolghadri   +49 more
wiley   +1 more source

The role of angiotensin I converting enzyme insertion/deletion polymorphism in the severity and outcomes of COVID-19 patients

Frontiers in Genetics, 2022
The pandemic of coronavirus disease in 2019 has led to a global crisis. COVID-19 shows distinct clinical manifestations of the severity of symptoms. Numerous patients with no associated risk factors demonstrate acute respiratory distress syndrome (ARDS).
Mitra Rezaei, Mitra Rezaei, Hadiseh Mohammadpour, Mahya Eftekhari, Mihan Pourabdollah, Farinaz Nasr Azadani, Payam Tabarsi, Majid Marjani, Seyed Ali Ziai   +8 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jurg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +28 more
wiley   +1 more source

Neoehrlichia mikurensis—An emerging opportunistic tick‐borne infection in immunosuppressed patients

Journal of Internal Medicine, Volume 293, Issue 6, Page 782-790, June 2023., 2023
Abstract Background Neoehrlichia mikurensis (N. mikurensis) is a newly discovered tick‐borne pathogen that can inflict life‐threatening illness in immunocompromised patients. N. mikurensis infection is only detectable by polymerase chain reaction (PCR)‐based methodologies. We describe three distinct clinical manifestations of N.
Rosa M. M. Gynthersen, Christen Rune Stensvold, Signe Ledou Nielsen, Holger Jon Møller, Henrik Vedel Nielsen, Anne‐Mette Lebech, Jeppe Romme Christensen, Helene Mens, Daniel El Fassi   +8 more
wiley   +1 more source