Results 11 to 20 of about 6,534 (185)

Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia

Journal of Extracellular Vesicles, Volume 12, Issue 12, December 2023., 2023
Abstract Periodontitis is a chronic inflammatory disease caused by periodontal pathogens in subgingival plaque and is associated with systemic inflammatory diseases. Extracellular vesicles (EVs) released from host cells and pathogens carry a variety of biological molecules and are of interest for their role in disease progression and as diagnostic ...
Younggap Lim, Hyun Young Kim, Dohyun Han, Bong‐Kyu Choi   +3 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets

British Journal of Pharmacology, Volume 180, Issue S2, Page S1-S22, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, O. Peter Buneman, Elena Faccenda, Simon D. Harding, Michael Spedding, John A. Cidlowski, Doriano Fabbro, Anthony P. Davenport, Jörg Striessnig, Jamie A. Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi P. Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill Martemyanov, Luke D. Mascarenhas, Harrison McNabb, Carolina Montañez‐Miranda, Osita Ogujiofor, Hoa Phan, David L. Roman, Vincent Shaw, Benita Sjogren, Christopher Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie Sutton, Menbere Wendimu, Thomas Wilkie, Keqiang Xie, Qian Zhang, Yalda Zolghadri   +49 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jurg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +28 more
wiley   +1 more source

Neoehrlichia mikurensis—An emerging opportunistic tick‐borne infection in immunosuppressed patients

Journal of Internal Medicine, Volume 293, Issue 6, Page 782-790, June 2023., 2023
Abstract Background Neoehrlichia mikurensis (N. mikurensis) is a newly discovered tick‐borne pathogen that can inflict life‐threatening illness in immunocompromised patients. N. mikurensis infection is only detectable by polymerase chain reaction (PCR)‐based methodologies. We describe three distinct clinical manifestations of N.
Rosa M. M. Gynthersen, Christen Rune Stensvold, Signe Ledou Nielsen, Holger Jon Møller, Henrik Vedel Nielsen, Anne‐Mette Lebech, Jeppe Romme Christensen, Helene Mens, Daniel El Fassi   +8 more
wiley   +1 more source

Stimulation of ACE inhibitory and improving α‐amylase and α‐glucosidase and antioxidant activities of semi‐prepared and dry soup by incorporating with date kernel powder

Food Science &Nutrition, Volume 11, Issue 3, Page 1342-1353, March 2023., 2023
Date kernel powder (DKP) could be considered as the potential functional ingredient in healthy food products. DKP improved α‐amylase and α‐glucosidase and antioxidant activities of semi‐prepared and dry soup (SPDS). SPDS with improved nutritional properties was provided using DKP incorporation.
Maryam Mousavi, Vajiheh Fadaei, Behrouz Akbari‐adergani   +2 more
wiley   +1 more source

Taxonomical and functional changes in COVID‐19 faecal microbiome could be related to SARS‐CoV‐2 faecal load

Environmental Microbiology, Volume 24, Issue 9, Page 4299-4316, September 2022., 2022
Summary Since the beginning of the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) the gastrointestinal (GI) tract has emerged as an important organ influencing the propensity to and potentially the severity of the related COVID‐19 disease.
Lucia Grenga, Olivier Pible, Guylaine Miotello, Karen Culotta, Sylvie Ruat, Marie‐Anne Roncato, Fabienne Gas, Laurent Bellanger, Pierre‐Géraud Claret, Catherine Dunyach‐Remy, Didier Laureillard, Albert Sotto, Jean‐Philippe Lavigne, Jean Armengaud   +13 more
wiley   +1 more source

Structural and molecular characterization of paraventricular thalamic glucokinase‐expressing neuronal circuits in the mouse

Journal of Comparative Neurology, Volume 530, Issue 11, Page 1773-1949, August 2022., 2022
By using a genetically modified mouse model and viral tracing approaches, we mapped both the anterograde and the retrograde projections of a subpopulation of neurons in the anterior paraventricular thalamic nucleus, molecularly defined by the expression of glucokinase (GckaPVT).
Sevasti Gaspari, Simon Quenneville, Ana Rodriguez Sanchez‐Archidona, Bernard Thorens, Sophie Croizier   +4 more
wiley   +1 more source

Emerging roles of MT‐MMPs in embryonic development

Developmental Dynamics, Volume 251, Issue 2, Page 240-275, February 2022., 2022
Abstract Membrane‐type matrix metalloproteinases (MT‐MMPs) are cell membrane‐tethered proteinases that belong to the family of the MMPs. Apart from their roles in degradation of the extracellular milieu, MT‐MMPs are able to activate through proteolytic processing at the cell surface distinct molecules such as receptors, growth factors, cytokines ...
Natalia Moracho, Ana I. R. Learte, Emma Muñoz‐Sáez, Miguel A. Marchena, María A. Cid, Alicia G. Arroyo, Cristina Sánchez‐Camacho   +6 more
wiley   +1 more source

Pro‐atherogenic actions of signal transducer and activator of transcription 1 serine 727 phosphorylation in LDL receptor deficient mice via modulation of plaque inflammation

The FASEB Journal, Volume 35, Issue 10, October 2021., 2021
Abstract Atherosclerosis is a chronic inflammatory disorder of the vasculature regulated by cytokines. We have previously shown that extracellular signal‐regulated kinase‐1/2 (ERK1/2) plays an important role in serine 727 phosphorylation of signal transducer and activator of transcription‐1 (STAT1) transactivation domain, which is required for maximal ...
Wijdan Al‐Ahmadi, Thomas S. Webberley, Alex Joseph, Ffion Harris, Yee‐Hung Chan, Reem Alotibi, Jessica O. Williams, Alaa Alahmadi, Thomas Decker, Timothy R. Hughes, Dipak P. Ramji   +10 more
wiley   +1 more source

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]

, 2005
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Burnham, S., Isaac, R.E., Lee, A.J., Shirras, A.D., Smith, J.A.   +4 more
core   +4 more sources