Results 41 to 50 of about 113,934,450 (165)

Bioactive Peptide‐Enriched Requeson: A Functional Dairy Product From Whey Fermentation

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study presents the production of functional Requeson from whey using lactic fermentation. Proteolysis induced by Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus promotes the generation of bioactive peptides. The product is evaluated for antioxidant, ACE‐inhibitory, DPP‐IV inhibitory, mineral chelating, and antimicrobial ...
Luis‐Fernando Patlan‐Velázquez   +7 more
wiley   +1 more source

Peptidyl-prolyl isomerases : A full cast of critical actors in cardiovascular diseases [PDF]

open access: yes, 2015
Peptidyl-prolyl cis-trans-isomerases are a highly conserved family of immunophilins. The three peptidyl-prolyl cis-trans-isomerase subfamilies are cyclophilins, FK-506-binding proteins, and parvulins. Peptidyl-prolyl cis-trans-isomerases are expressed in
G.L. Perrucci   +5 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Introduction and Other Protein Targets

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S1-S23, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +51 more
wiley   +1 more source

Pericardial Parietal Mesothelial Cells: Source of the Angiotensin-Converting-Enzyme of the Bovine Pericardial Fluid

open access: yesArquivos Brasileiros de Cardiologia
Background: Angiotensin II (Ang II), the primary effector hormone of the renin-angiotensin system (RAS), acts systemically or locally, being produced by the action of angiotensin-converting-enzyme (ACE) on angiotensin I.
Ilsione Ribeiro de Sousa Filho   +5 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

Matching maternal and paternal experiences underpin molecular thermal acclimation

open access: yesMolecular Ecology, Volume 34, Issue 15, August 2025.
Abstract The environment experienced by one generation has the potential to affect the subsequent one through non‐genetic inheritance of parental effects. Since both mothers and fathers can influence their offspring, questions arise regarding how the maternal, paternal and offspring experiences integrate into the resulting phenotype.
L. C. Bonzi   +5 more
wiley   +1 more source

Structural and Functional Characterization of a Novel Family of Cyclophilins, the AquaCyps [PDF]

open access: yes, 2016
Cyclophilins are ubiquitous cis-trans-prolyl isomerases (PPIases) found in all kingdoms of life. Here, we identify a novel family of cyclophilins, termed AquaCyps, which specifically occurs in marine Alphaproteobacteria, but not in related terrestric ...
Timm Maier   +14 more
core   +2 more sources

Quantitative Characterization of Gene Regulatory Circuits Associated With Fungal Secondary Metabolism to Discover Novel Natural Products

open access: yesAdvanced Science, Volume 11, Issue 47, December 18, 2024.
An advanced microfluidic platform is created to enable precise characterization of complex multicellular fungal gene regulatory circuits (GRCs) at the single‐cell level. Quantification of GRCs involved in secondary metabolite production provides new insights into gene regulation of fungal secondary metabolism and highlights the potential of synthetic ...
Xinran Xu   +10 more
wiley   +1 more source

Effect of Reno vascular Hypertension Model on Spermatogenesis in Rat

open access: yesپزشکی بالینی ابن سینا, 2008
Introduction & Objective: Change in function of general and regional rennin- angiotensin system is the most important factor in cardiovascular disorders and essential hypertension.
Iraj Salehi   +2 more
doaj  

Multiomics analysis reveals the potential mechanism of high‐fat diet in dextran sulfate sodium‐induced colitis mice model

open access: yesFood Science &Nutrition, Volume 12, Issue 10, Page 8309-8323, October 2024.
HFD‐treated mice exhibited notable alternations in the structure and composition of the gut microbiota, with some of these alternations being associated with the pathogenesis of IBD. Analysis of the colon transcriptome revealed 11 hub genes and 7 hub pathways among control, DSS‐induced colitis, and HFD + DSS‐treated groups. Impact of HFD on DSS‐induced
Yuyang Zhao   +8 more
wiley   +1 more source

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