Results 11 to 20 of about 4,910 (132)

Stimulation of ACE inhibitory and improving α‐amylase and α‐glucosidase and antioxidant activities of semi‐prepared and dry soup by incorporating with date kernel powder

Food Science &Nutrition, Volume 11, Issue 3, Page 1342-1353, March 2023., 2023
Date kernel powder (DKP) could be considered as the potential functional ingredient in healthy food products. DKP improved α‐amylase and α‐glucosidase and antioxidant activities of semi‐prepared and dry soup (SPDS). SPDS with improved nutritional properties was provided using DKP incorporation.
Maryam Mousavi, Vajiheh Fadaei, Behrouz Akbari‐adergani   +2 more
wiley   +1 more source

Taxonomical and functional changes in COVID‐19 faecal microbiome could be related to SARS‐CoV‐2 faecal load

Environmental Microbiology, Volume 24, Issue 9, Page 4299-4316, September 2022., 2022
Summary Since the beginning of the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) the gastrointestinal (GI) tract has emerged as an important organ influencing the propensity to and potentially the severity of the related COVID‐19 disease.
Lucia Grenga, Olivier Pible, Guylaine Miotello, Karen Culotta, Sylvie Ruat, Marie‐Anne Roncato, Fabienne Gas, Laurent Bellanger, Pierre‐Géraud Claret, Catherine Dunyach‐Remy, Didier Laureillard, Albert Sotto, Jean‐Philippe Lavigne, Jean Armengaud   +13 more
wiley   +1 more source

Structural and molecular characterization of paraventricular thalamic glucokinase‐expressing neuronal circuits in the mouse

Journal of Comparative Neurology, Volume 530, Issue 11, Page 1773-1949, August 2022., 2022
By using a genetically modified mouse model and viral tracing approaches, we mapped both the anterograde and the retrograde projections of a subpopulation of neurons in the anterior paraventricular thalamic nucleus, molecularly defined by the expression of glucokinase (GckaPVT).
Sevasti Gaspari, Simon Quenneville, Ana Rodriguez Sanchez‐Archidona, Bernard Thorens, Sophie Croizier   +4 more
wiley   +1 more source

Emerging roles of MT‐MMPs in embryonic development

Developmental Dynamics, Volume 251, Issue 2, Page 240-275, February 2022., 2022
Abstract Membrane‐type matrix metalloproteinases (MT‐MMPs) are cell membrane‐tethered proteinases that belong to the family of the MMPs. Apart from their roles in degradation of the extracellular milieu, MT‐MMPs are able to activate through proteolytic processing at the cell surface distinct molecules such as receptors, growth factors, cytokines ...
Natalia Moracho, Ana I. R. Learte, Emma Muñoz‐Sáez, Miguel A. Marchena, María A. Cid, Alicia G. Arroyo, Cristina Sánchez‐Camacho   +6 more
wiley   +1 more source

Pro‐atherogenic actions of signal transducer and activator of transcription 1 serine 727 phosphorylation in LDL receptor deficient mice via modulation of plaque inflammation

The FASEB Journal, Volume 35, Issue 10, October 2021., 2021
Abstract Atherosclerosis is a chronic inflammatory disorder of the vasculature regulated by cytokines. We have previously shown that extracellular signal‐regulated kinase‐1/2 (ERK1/2) plays an important role in serine 727 phosphorylation of signal transducer and activator of transcription‐1 (STAT1) transactivation domain, which is required for maximal ...
Wijdan Al‐Ahmadi, Thomas S. Webberley, Alex Joseph, Ffion Harris, Yee‐Hung Chan, Reem Alotibi, Jessica O. Williams, Alaa Alahmadi, Thomas Decker, Timothy R. Hughes, Dipak P. Ramji   +10 more
wiley   +1 more source

Diferenças entre os sexos na atividade da enzima conversora de angiotensina e na pressão arterial em crianças: um estudo observacional Gender differences in serum angiotensin-converting enzyme activity and blood pressure in children: an observational study

Arquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: A enzima conversora da angiotensina (ECA), principal enzima do sistema renina-angiotensina (SRA), desempenha um papel importante na regulação da pressão arterial. A atividade enzimática da ECA e sua relação com a pressão arterial (PA) durante
Patricia Landazuri, Claudia Granobles, Nelsy Loango   +2 more
doaj   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets

British Journal of Pharmacology, Volume 178, Issue S1, Page S1-S26, October 2021., 2021
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets ...
Stephen P H Alexander, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, O Peter Buneman, John A Cidlowski, Arthur Christopoulos, Anthony P Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, Jamie A Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi P. Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill Martemyanov, Luke D. Mascarenhas, Harrison McNabb, Carolina Montañez‐Miranda, Osita Ogujiofor, Hoa Phan, David L. Roman, Vincent Shaw, Benita Sjogren, Christopher Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie Sutton, Menbere Wendimu, Thomas Wilkie, Keqiang Xie, Qian Zhang, Yalda Zolghadri   +52 more
wiley   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes

British Journal of Pharmacology, Volume 178, Issue S1, Page S313-S411, October 2021., 2021
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets ...
Stephen P H Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Doris Koesling, Rennolds Ostrom, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Michael Russwurm, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +32 more
wiley   +1 more source

Sarcoidosis: old certainties and new perspectives

Italian Journal of Medicine, 2012
Introduction Sarcoidosis is the paradigm of the internistic disease. It virtually affects every organ and tissue and is characterized by the presence of noncaseating granulomas.
Claudio Tana, Marco Tana, Andrea Mezzetti, Cosima Schiavone   +3 more
doaj   +1 more source

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

Biomolecules, 2020
Caffeic acid (CA) and its derivatives caffeic acid phenethyl ester (CAPE) and chlorogenic acid (CGA) are phenolic compounds of plant origin with a wide range of biological activities. Here, we identify and characterize their inhibitory properties against
Liza Ulčakar, Marko Novinec
doaj   +1 more source