Association between the polymorphisms of angiotensin converting enzyme (Peptidyl-Dipeptidase A) INDEL mutation (I/D) and Angiotensin II type I receptor (A1166C) and breast cancer among post menopausal Egyptian females [PDF]
Renin angiotensin system (RAS) is involved in the regulation of cardiovascular homeostasis. Angiotensin (Ang II) is converted from angiotensin I via angiotensin converting enzyme (ACE). Ang II exerts its effects by binding to two types of receptors; AT1R
Rania Mohamed El Sharkawy+4 more
doaj +2 more sources
Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor. [PDF]
Masuyer G+4 more
europepmc +3 more sources
The metabolism of neuropeptides. Neurokinin A (substance K) is a substrate for endopeptidase-24.11 but not for peptidyl dipeptidase A (angiotensin-converting enzyme) [PDF]
A J Kenny, A J Turner, N M Hooper
core +3 more sources
Sarcoidosis: old certainties and new perspectives
Introduction Sarcoidosis is the paradigm of the internistic disease. It virtually affects every organ and tissue and is characterized by the presence of noncaseating granulomas.
Claudio Tana+3 more
doaj +1 more source
Characterization of substrate specificity and novel autoprocessing mechanism of dipeptidase A from Prevotella intermedia [PDF]
Prevotella intermedia, a gram-negative anaerobic rod, is frequently observed in subgingival polymicrobial biofilm from adults with chronic periodontitis. Peptidases in periodontopathic bacteria are considered to function as etiological reagents.
Kobayakawa Takeshi+4 more
core +2 more sources
Angiotensin-I-Converting Enzyme and its Relatives [PDF]
Angiotensin-I-converting enzyme (ACE) is a monomeric, membrane-bound, zinc- and chloridedependent peptidyl dipeptidase that catalyzes the conversion of the decapeptide angiotensin I to the octapeptide angiotensin II, by removing a carboxy-terminal ...
Riordan, James Francis
core +1 more source
A proteinaceous organic matrix regulates carbonate mineral production in the marine teleost intestine [PDF]
Marine teleost fish produce CaCO(3) in their intestine as part of their osmoregulatory strategy. This precipitation is critical for rehydration and survival of the largest vertebrate group on earth, yet the molecular mechanisms that regulate this ...
Adrian Pelin+6 more
core +2 more sources
Cathepsin B carboxydipeptidase specificity analysis using internally quenched fluorescent peptides [PDF]
We have examined in detail the specificity of the subsites S-1, S-2, S-1' and S-2' for the carboxydipeptidase activity of cathepsin B by synthesizing and assaying four series of internally quenched fluorescent peptides based on the sequence Dnp-GFRFW-OH,
Carmona, Adriana Karaoglanovic+4 more
core +2 more sources
Shapes and Positions of Black Hole Shadows in Accretion Disks and Spin Parameters of Black Holes [PDF]
Can we determine a spin parameter of a black hole by observation of a black hole shadow in an accretion disk? In order to answer this question, we make a qualitative analysis and a quantitative analysis of a shape and a position of a black hole shadow casted by a rotating black hole on an optically thick accretion disk and its dependence on an angular ...
arxiv +1 more source
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Enzymes [PDF]
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
,+11 more
core +15 more sources