Results 81 to 90 of about 33,890 (233)

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

open access: yesPlant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Distribution of dwell times of a ribosome: effects of infidelity, kinetic proofreading and ribosome crowding

open access: yes, 2011
Ribosome is a molecular machine that polymerizes a protein where the sequence of the amino acid residues, the monomers of the protein, is dictated by the sequence of codons (triplets of nucleotides) on a messenger RNA (mRNA) that serves as the template ...
Ajeet K Sharma   +10 more
core   +1 more source

PRMT7 Is a Member of the Protein Arginine Methyltransferase Family with a Distinct Substrate Specificity [PDF]

open access: yes, 2004
We have identified a mammalian arginine N-methyltransferase, PRMT7, that can catalyze the formation of ω-N^G-monomethylarginine in peptides. This protein is encoded by a gene on human chromosome 16q22.1 (human locus AK001502).
Clarke, Steven   +3 more
core   +1 more source

Protein engineering strategies to optimise recombinant product synthesis and accumulation in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, Volume 24, Issue 1, Page 31-43, January 2026.
Summary In plant molecular farming, recombinant products include traditional protein targets, such as antibodies, antigens, and enzymes, but also increasingly refers to high‐value peptides, and small molecules produced by heterologous enzymatic pathways.
Maxim D. Harding, Frank Sainsbury
wiley   +1 more source

Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current Solutions

open access: yesAntibiotics, 2016
Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety.
George P. Dinos   +7 more
doaj   +1 more source

Translational control in plants: from basic mechanisms to environmental and developmental responses

open access: yesThe Plant Journal, Volume 125, Issue 1, January 2026.
SUMMARY Protein synthesis is an essential process for all living organisms and is tightly regulated to ensure the proper production of proteins needed for growth, development, and stress responses. As sessile organisms, plants have evolved distinct mechanisms to regulate translation, allowing them to adapt to their environment.
Jade Lyons   +3 more
wiley   +1 more source

Collagens - structure, function and biosynthesis. [PDF]

open access: yes, 2003
The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Aigner, T, Gelse, K, Poschl, E
core   +1 more source

Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size

open access: yesCell Reports, 2016
Macrolide antibiotic binding to the ribosome inhibits catalysis of peptide bond formation between specific donor and acceptor substrates. Why particular reactions are problematic for the macrolide-bound ribosome remains unclear.
Shanmugapriya Sothiselvam   +6 more
doaj   +1 more source

Bactobolin Resistance Is Conferred by Mutations in the L2 Ribosomal Protein [PDF]

open access: yes, 2012
Burkholderia thailandensis produces a family of polyketide-peptide molecules called bactobolins, some of which are potent antibiotics. We found that growth of B.
Carr, Gavin   +9 more
core   +2 more sources

Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs. [PDF]

open access: yesPLoS ONE, 2008
6-Aminophenanthridine (6AP) and Guanabenz (GA, a drug currently in use for the treatment of hypertension) were isolated as antiprion drugs using a yeast-based assay.
Déborah Tribouillard-Tanvier   +18 more
doaj   +1 more source

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