Results 171 to 180 of about 2,850,818 (357)
Traumatic Stress, Perceived Global Stress, and Life Events: Prospectively Predicting Quality of Life in Breast Cancer Patients.
, 2005 Deanna M. Golden‐Kreutz, Lisa M. Thornton, Sharla Wells‐Di Gregorio, Georita Marie Frierson, Heather Jim, Kristen M. Carpenter, Rebecca A. Shelby, Barbara L. Andersen +7 moreopenalex +1 more sourceImproving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann +15 morewiley +1 more sourceClass IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio +13 morewiley +1 more sourceImpact of prehabilitation on patient-perceived quality of recovery after surgery: prospective cohort study. [PDF]
BJS OpenDana F, González-Colom R, Tena B, Capitán D, Momblan D, Campero B, García Lopez L, Ubré M, Sebio-García R, Zabalegui A, Martinez-Palli G, Hospital Clinic de Barcelona Prehabilitation Group
. +11 moreeuropepmc +1 more sourceInvestigating the Effect of Perceived Healthcare Products Quality and Brand Image on Brand Usage Moderated by Brand Trust [PDF]
Mayar Farrag, Y Ai, M Rahman, M Newaz, M Gazi, M Rahaman, A Mamun, X Chen, L Amelia, A Ayani, G Assaker, S Atulkar, T Assauri, S Alwi, S Alwi, N Asshidin, A Bayu, M Basha, M Shaari, P Nair, R Blendon, C Desroches, M Brodie, J Benson, A Rosen, E Schneider, D Altman, P Cuong, Y Chen, A Cakmak, S Chakraborty, A Sheppard, R Chinomona, R Ellis, R Ellis, T Yuce, D Hewitt, R Merkow, C Kinnier, J Johnson, K Bilimoria, T Erkmen, M Hancer, A Erci, J Fidler, X Han, J Hanaysha, P Hewer, K Hafiz, N Ali, K Hafiz, N Ali, S Hegner, C Jevons, C Heerden, G Puth, M Irshad, A Komari, K Keller, F Konuk, P Kotler, G Armstrong, P Kotler, H Lee, G Lau, S Lee, D Lichtenstein, R Netemeyer, S Burton, D Martn-Consuegra, P Martnez, R Mcdonald, M Nogueira, N Antnio, A Narwal, G Kaur, J Nam, Y Ekinci, G Whyatt, R Oliver, R Pappu, P Quester, L Petruzzellis, R Priem, J Rosenstein, S Rehman, S Rahi, S Roy, L Eunkyoung, W Kwon, U Subramanian, P Rauyruen, K Miller, J Romaniuk, B Sharp, D Sabelhaus, J Sallis, N Owen, E Fisher, M Shafiee +99 moreopenalex +1 more sourceEffect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees +6 morewiley +1 more source
