Results 171 to 180 of about 10,943,386 (377)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
JPPI (Jurnal Penelitian Pendidikan Indonesia)Semakin dominannya lingkungan digital dalam perilaku konsumen, penelitian dapat mengeksplorasi lebih lanjut bagaimana interaksi online, seperti platform media sosial, memengaruhi persepsi konsumen terhadap produk skincare dan keputusan pembelian mereka ...
Estefanie Dwitasreshi Manurung +1 more
doaj +1 more source
An Empirical Test of Customer Retention-Perceived Quality Link: Strategic Management Implications
, 1970 Godwin Onyeaso, Chris Adalikwu
openalex +2 more sources
Structural equation modeling of eBankQual scale: a study of E-Banking in India [PDF]
This study assesses the relationship between perceived quality, brand perception and perceived value with satisfaction. For the data analysis structural equation modeling (SEM) method and path analysis method were used. A result indicates that, eBankQual
Kumbhar, Vijay
core +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Perceived environmental housing quality and wellbeing of movers [PDF]
, 2001 Sonja Kahlmeier
openalex +1 more source
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
Enhancing the Perceived Quality of a Vehicle Sliding Door Inner Handle Concept Design
Applied SciencesCustomers can always verbalize their feelings about a product, but engineers can only methodically improve what they measure in a robust and reliable manner. There is a need to convert customer needs into technical parameters. The aim of this study is to
Emel Unlukal Ilhan +2 more
doaj +1 more source