Results 161 to 170 of about 8,582,216 (300)
, 2015 Gudmund Grønhaug,1 Jon Hagfors,2 Ingebjørg Borch,2 Nina Østerås,1 Kåre Birger Hagen11National Advisory Unit on Rehabilitation in Rheumatology, Diakonhjemmet Hospital, 2Norwegian Rheumatism Association, Oslo ...
Hagfors J +4 more
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Physician Consultation Time and Perceived Quality of Outpatient Care for New Cancer Patients in Korea: An Experimental Vignette Survey of the General Public and Physicians. [PDF]
J Korean Med SciPark JS, Lee MH, Kim SY, Do YK.
europepmc +1 more source
Goals Affect the Perceived Quality of Explanations.
, 2015 Do people evaluate the quality of explanations differently depending on their goals? In particular, are explanations of different kinds (formal, mechanistic, teleological) judged differently depending on the future judgments the evaluator anticipates making?
Vasilyeva, Nadya +2 more
openaire +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Self-Perceived Quality of Life and Physical Activity Levels Through Accelerometry in Young People with Intellectual Disabilities. [PDF]
Healthcare (Basel)Menchén-Rubio M +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Exploring Women's Perceived Quality of Antenatal Care: A Cross-Sectional Study in The Netherlands. [PDF]
Int J Environ Res Public HealthCellissen E +4 more
europepmc +1 more source