Results 171 to 180 of about 657,592 (268)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Weight loss and self-perceived quality of life following laparoscopic Roux-en-Y gastric bypass: is it important? [PDF]

Arq Bras Cir Dig
Castro GRA, Macedo LD, Ferri JVV, Vulcanis IB, Andrade DP, Sadowski JA, Bastos ELS, Marchesini JCD.   +7 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Perinatal healthcare access, perceived quality, and preferences among historically underrepresented mother-infant dyads: a mixed methods study. [PDF]

BMC Pregnancy Childbirth
Amodio NC, Cueto V, Znamierowski E, Firoz T, Taylor SN, Ayande REA, Sude L, Rosenberg J.   +7 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

The relationship between consultation modality and mental health professional type and perceived quality of care and mental health outcomes: A comparison between employed and unemployed individuals. [PDF]

PLOS Ment Health
Sathananthan A, Balakrishnar K, Premji R, Nowrouzi-Kia B.   +3 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Perceived quality of padel users: adaptation and validation of the QPadel assessment tool. [PDF]

Front Sports Act Living
Fernández Martínez N, Gálvez-Ruiz P, Gómez Chacón R, Lara-Bocanegra A.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The Role of Sociodemographic Characteristics and Social Determinants of Health in Influencing the Perceived Quality of Patient-Provider Communication. [PDF]

Nurs Rep
Eldawy N, Kaleem S, Jhumkhawala V, Okwaraji G, Jimenez S, Sohmer J, Mejia M, Kitsantas P, Sacca L.   +8 more
europepmc   +1 more source