Results 81 to 90 of about 1,039,528 (244)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Performances de reproduction de l'élevage canin en France
, 2015 Les données enregistrées par 5667 éleveurs dans un logiciel privé sur 46393 périodes de chaleur de 27221 chiennes de 248 races et 204537 chiots ont permis de décrire les performances de l'élevage canin français. Le taux de gestation par cycle était de 87,8%, 6,8% des chiennes gravides ont avorté.
openaire +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Volume visualization of time-varying data using parallel, multiresolution and adaptive-resolution techniques [PDF]
, 2006 This paper presents a parallel rendering approach that allows high-quality visualization of large time-varying volume datasets. Multiresolution and adaptive-resolution techniques are also incorporated to improve the efficiency of the rendering.
Shams, Sadaf
core +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Optimal adult growth of Daphnia in a seasonal environment [PDF]
, 1993 1. The cladoceran Daphnia serves as an example of an iteroparous organism, with overlapping generations, that is capable of substantial adult growth. The life history of Daphnia was modelled as the consequence of a series of decisions about allocation of
Gabriel, Wilfried, Taylor, B. E.
core
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Leslislating in the Face of New Technology: Copyright Laws for the Digital Age [PDF]
, 1996 This Note discusses the agendas and proposals of different countries with respect to copyright regulation in the digital age. Part I discusses the present state of copyright law in the United States, the United Kingdom, and the European Community. Part I
Morano, Michael F.
core +1 more source