Results 181 to 190 of about 3,925,092 (294)

Efficacy of fetal left ventricular modified myocardial performance index in predicting adverse perinatal outcomes in intrahepatic cholestasis of pregnancy. [PDF]

Rev Assoc Med Bras (1992), 2022
Gök K, Takmaz T, Köse O, Kapudere B, Tüten N, Bostancı MS, Özden S.   +6 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A novel hole performance index to evaluate the hole geometry and drilling time in the electrochemical drilling process. [PDF]

PLoS One
Tosun N, Özerkan HB, Çoğun C, Cep R.
europepmc   +1 more source

Cardiac time intervals and myocardial performance index for prediction of twin-twin transfusion syndrome. [PDF]

Prenat Diagn, 2021
Gijtenbeek M, Eschbach SJ, Middeldorp JM, Klumper FJCM, Slaghekke F, Oepkes D, Haak MC.   +6 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The Significance of the Myocardial Performance Index and Fetal Doppler Abnormalities in Growth-Restricted Fetuses: A Systematic Review of the Literature. [PDF]

J Clin Med
Czapska AH, Kosińska-Kaczyńska K.
europepmc   +1 more source

Gross domestic product and logistics performance index drive the world trade: A study based on all continents. [PDF]

PLoS One, 2022
Jayathilaka R, Jayawardhana C, Embogama N, Jayasooriya S, Karunarathna N, Gamage T, Kuruppu N.   +6 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Myocardial Performance Index to assess cardiac function in autoimmune connective tissue disease: a systematic review and meta-analysis. [PDF]

Lupus Sci Med
Hidayat R, Nasution SA, Parlindungan F, Dalimunthe NN, Alvianto S, Widjanarko ND, Kultsum U, Efendi C, Gotama Y.   +8 more
europepmc   +1 more source

Assessment of myocardial performance index in late-onset fetal growth restriction. [PDF]

Nagoya J Med Sci, 2021
Nguyen TTN, Kotani T, Imai K, Ushida T, Moriyama Y, Kobayashi T, Niimi K, Sumigama S, Yamamoto E, Vo VD, Le MT, Le LH, Nguyen DN, Nguyen VQH, Truong QV, Cao NT, Kikkawa F.   +16 more
europepmc   +1 more source