Internal State of Vesicles Affects Higher Order State of Vesicle Assembly and Interaction. [PDF]
ACS OmegaHoller S, Casiraghi F, Hanczyc MM.
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Sterols in plant biology <i>-</i> Advances in studying membrane dynamics. [PDF]
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VAPB is a negative regulator of STING-mediated innate immune signaling. [PDF]
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Clostridium perfringens: A Potential Pathobiont in Inflammatory Bowel Disease. [PDF]
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Measuring Mitochondrial Substrate Flux in Recombinant Perfringolysin O-Permeabilized Cells
Journal of Visualized Experiments, 2021Mitochondrial substrate flux is a distinguishing characteristic of each cell type, and changes in its components such as transporters, channels, or enzymes are involved in the pathogenesis of several diseases. Mitochondrial substrate flux can be studied using intact cells, permeabilized cells, or isolated mitochondria.
Moustafa, Elkalaf +5 more
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Age-development changes in susceptibility of erythrocytes to perfringolysin O
Mechanisms of Ageing and Development, 1982Susceptibility to perfringolysin O of erythrocytes from mice of different ages was examined. Erythrocytes of mice younger than 5 weeks' old were more resistant to the toxin than those of young adult and adult mice. Erythrocytes of aged mice were about 3.5 times more susceptible to the toxin than erythrocytes from 4-week-old mice.
Saito, M +5 more
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Activation of phosphatidic acid metabolism of human erythrocyte membranes by perfringolysin O
Biochemical and Biophysical Research Communications, 1986The effect of perfringolysin O on the lipid metabolism of human erythrocyte membranes was investigated. Erythrocytes were prelabeled with [3H]arachidonic acid and [32P]inorganic phosphate. In the presence of calcium ion(5.5 mM), the effect of perfringolysin O on lipid metabolism was very similar to that of an calcium-ionophore A23187. In the absence of
M, Saito +4 more
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Ring formation of perfringolysin o as revealed by negative stain electron microscopy
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1979Abstract Perfringolysin O revealed ring- and arc-shaped structures in the absence of cholesterol by negative staining electron microscopy, while before activation with cysteine it showed indistinct arcs and irregularly curved sticks but no rings. These structures were observed only at high concentrations (more than 17 000 hemolytic units per ml) and ...
K, Mitsui +4 more
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Effects of cholesterol evulsion on susceptibility to perfringolysin o of human erythrocytes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1982Human erythrocytes preincubated with a phosphatidylcholine suspension (preincubated cells) showed decreased susceptibility to perfringolysin O, the decrease being strongly affected by preincubation time and temperature, and the phosphatidyl choline concentration.
K, Mitsui, Y, Saeki, J, Hase
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Perfringolysin O, a cholesterol-binding cytolysin, as a probe for lipid rafts
Anaerobe, 2004Gaining an understanding of the structural and functional roles of cholesterol in membrane lipid rafts is a critical issue in studies on cellular signaling and because of the possible involvement of lipid rafts in various diseases. We have focused on the potential of perfringolysin O (theta-toxin), a cholesterol-binding cytolysin produced by ...
Yoshiko, Ohno-Iwashita +7 more
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