Results 221 to 230 of about 27,494 (299)

RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment

MedComm, Volume 7, Issue 7, July 2026.
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li, Yating Sun, Shuibin Lin, Quan Yuan   +3 more
wiley   +1 more source

CO₂ inhalation enhances pericyte-mediated neurovascular protection in ischemic stroke and remains safe in hemorrhagic stroke. [PDF]

J Cereb Blood Flow Metab
Yoon CE, Jung JW, Kim YB, Song J, Joo H, Kim B, Kwon I, Yoon SS, Kim JS, Choi HY, Kim YD, Heo JH, Nam HS.   +12 more
europepmc   +1 more source

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

Brain Pathology, Volume 36, Issue 4, July 2026.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu, Yanan Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

The Role of Angiogenesis in Breast Cancer and Obesity: Unravelling the Connection. [PDF]

Int J Breast Cancer
Sikuza YOK, Basson C, Oberholzer N, Ambele MA.   +3 more
europepmc   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, Volume 36, Issue 4, July 2026.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Neurovascular dysfunction in the development and progression of neuroinflammatory diseases. [PDF]

Front Cell Neurosci
Gowdy J, Ahn J, Miller RH, Islam Y.
europepmc   +1 more source

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

Brain Pathology, Volume 36, Issue 4, July 2026.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato, Satoru Miyawaki, Yu Sakai, Kenta Ohara, Yu Teranishi, Yudai Hirano, Motoyuki Umekawa, Takahiro Tsuchiya, Shotaro Ogawa, So Hirata, Hiroki Hongo, Hideaki Ono, Daisuke Komura, Tetsuo Ushiku, Shumpei Ishikawa, Nobuhito Saito   +15 more
wiley   +1 more source

Targeting angiogenesis: Lessons from 25 years of normalizing tumor vasculature. [PDF]

Cell
Subudhi S, Lee S, Jain RK.
europepmc   +1 more source

RNA‐based CLEM (RCLEM) bridging RNA localisation and ultrastructural mapping in 3D

Journal of Microscopy, Volume 303, Issue 1, Page 120-131, July 2026.
Abstract Spatial transcriptomics and in situ hybridisation techniques have become essential for contextualising single‐cell RNA sequencing (scRNA‐seq) data by mapping cell type– and state–specific mRNA expression within intact tissues. Beyond validating scRNA‐seq predictions, these spatial methods provide critical insight into the localisation of ...
Daan Verhaege, Lore Van Acker, Camille Wagner, Yentl Van den Berghe, Jérémy Verbeke, Martin Guilliams, Anna Kremer, Lien Van Hoecke, Roosmarijn E Vandenbroucke   +8 more
wiley   +1 more source