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Pericyte–fibroblast transition promotes tumor growth and metastasis
Proceedings of the National Academy of Sciences of the United States of America, 2016 Vascular pericytes, an important cellular component in the tumor microenvironment, are often associated with tumor vasculatures, and their functions in cancer invasion and metastasis are poorly understood.
Giulio Cossu +2 more
exaly +7 more sources
Journal of Cerebral Blood Flow and Metabolism, 2016 Pericytes, spatially isolated contractile cells on capillaries, have been reported to control cerebral blood flow physiologically, and to limit blood flow after ischaemia by constricting capillaries and then dying. Paradoxically, a recent paper dismisses
Catherine Hall +2 more
exaly +3 more sources
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Pflügers Archiv - European Journal of Physiology, 2013
Pericytes in the retina differ from pericytes in many other organs by their high density and their cooperative role in the neurovascular unit. Their diverse ontogeny and the fact that not one pericyte marker identifies the entire population suggest also functional plurality in the retina, including invading cells of mesenchymal origin.
Frederick, Pfister +3 more
openaire +2 more sources
Pericytes in the retina differ from pericytes in many other organs by their high density and their cooperative role in the neurovascular unit. Their diverse ontogeny and the fact that not one pericyte marker identifies the entire population suggest also functional plurality in the retina, including invading cells of mesenchymal origin.
Frederick, Pfister +3 more
openaire +2 more sources
The FASEB Journal, 1993
Endothelial cells are the primary physical barrier between blood and tissue in microvessels. The other capillary and post‐capillary venule wall cell is the pericyte. The literature on the biology of endothelium is appreciable but less is known about pericytes.
D, Shepro, N M, Morel
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Endothelial cells are the primary physical barrier between blood and tissue in microvessels. The other capillary and post‐capillary venule wall cell is the pericyte. The literature on the biology of endothelium is appreciable but less is known about pericytes.
D, Shepro, N M, Morel
openaire +2 more sources
2019
Pericytes are pluripotent cells found in the vascular wall of both capillaries and large blood vessels. Pericytes are highly heterogeneous cells in terms of phenotype, tissue distribution, origin and functions, and they play an important role in the regulation of vascular morphogenesis and function.
Volha, Summerhill, Alexander, Orekhov
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Pericytes are pluripotent cells found in the vascular wall of both capillaries and large blood vessels. Pericytes are highly heterogeneous cells in terms of phenotype, tissue distribution, origin and functions, and they play an important role in the regulation of vascular morphogenesis and function.
Volha, Summerhill, Alexander, Orekhov
openaire +2 more sources
2019
Pericytes have long been known to contribute indirectly to tumour growth by regulating angiogenesis. Thus, remodelling tumour blood vessels to maintain blood supply is critical for continued tumour growth. A role for pericytes in restricting leakage of tumour cells through blood vessels has also become evident given that adequate pericyte coverage of ...
Pieterse, Z., Sinha, D., Kaur, Pritinder
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Pericytes have long been known to contribute indirectly to tumour growth by regulating angiogenesis. Thus, remodelling tumour blood vessels to maintain blood supply is critical for continued tumour growth. A role for pericytes in restricting leakage of tumour cells through blood vessels has also become evident given that adequate pericyte coverage of ...
Pieterse, Z., Sinha, D., Kaur, Pritinder
openaire +3 more sources
2019
This review chapter describes the current knowledge about the nature of pericytes in the gut, their interaction with endothelial cells in blood vessels, and their pathophysiological functions in the setting of chronic liver disease. In particular, it focuses on the role of these vascular cell types and related molecular signaling pathways in ...
Marta, Ramirez +3 more
openaire +2 more sources
This review chapter describes the current knowledge about the nature of pericytes in the gut, their interaction with endothelial cells in blood vessels, and their pathophysiological functions in the setting of chronic liver disease. In particular, it focuses on the role of these vascular cell types and related molecular signaling pathways in ...
Marta, Ramirez +3 more
openaire +2 more sources