Results 121 to 130 of about 5,812 (218)
Molecular Profiles of Pyramidal Neurons in the Superior Temporal Cortex in Schizophrenia [PDF]
, 2014 Disrupted synchronized oscillatory firing of pyramidal neuronal networks in the cerebral cortex in the gamma frequency band (i.e., 30–100 Hz) mediates many of the cognitive deficits and symptoms of schizophrenia.
Goldstein, Jill M. +11 more
core +2 more sources
iScienceSummary: Visual cortical plasticity is high during early life, but gradually decreases with development. This is due to the Otx2-driven maturation of intracortical inhibition that parallels the condensation of extracellular matrix components into ...
Dmytro Shmal +4 more
doaj +1 more source
The Mechanisms of Chondroitin Sulphate Lyases Treatment in Promotion of Axonal Growth [PDF]
, 2012 Poster PresentationIn Injured nerves, chondroitin sulphate (CS) is upregulated forming barriers with astrocytes/fibroblasts and other extracellular matrix molecules, and thereby hampering nerve regeneration.
Chan, YS, Shum, DKY, Tam, KW
core
Structural and Functional Aberrations in the Cerebral Cortex of Tenascin-C Deficient Mice [PDF]
, 2017 The extracellular matrix glycoprotein tenascin-C (TNC) has been implicated in neural development and plasticity but many of its functions in vivo remain obscure. Here we addressed the question as to whether the constitutive absence of TNC in mice affects
Irintchev, Andrey +4 more
core
Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type” neutral N-glycans [PDF]
, 2017 As a member of the tenascin family of extracellular matrix glycoproteins, tenascin-R is located exclusively in the CNS. It is believed to play a role in myelination and axonal stabilization and, through repulsive properties, may contribute to the lack of
Dwek, Raymond A. +6 more
core
Perineuronal nets in neurodegeneration
Oncotarget, 2016 Lemarchant, Sighild +2 more
openaire +2 more sources
Neuroplasticity and amblyopia: vision at the balance point [PDF]
, 2017 Purpose of review: New insights into triggers and brakes of plasticity in the visual system are being translated into new treatment approaches which may improve outcomes not only in children, but also in adults.
Dahlmann-Noor, AH +2 more
core
Perineuronal Net Microscopy: From Brain Pathology to Artificial Intelligence
International Journal of Molecular SciencesPerineuronal nets (PNN) are a special highly structured type of extracellular matrix encapsulating synapses on large populations of CNS neurons. PNN undergo structural changes in schizophrenia, epilepsy, Alzheimer’s disease, stroke, post-traumatic conditions, and some other brain disorders.
Mikhail Paveliev +9 more
openaire +2 more sources
Analysis of perineuronal net morphology and perineuronal synaptic reorganization during stroke recovery [PDF]
Perineuronal nets (PNNs) are specialized, mesh-like structures of the brain's extracellular matrix (ECM) that enwrap parvalbumin-positive (PV+) interneurons in the cortex. Despite their known role in neuroplasticity regulation, the limited resolution of conventional microscopy hindered quantitative analysis of PNN morphology.
openaire +2 more sources
Journal of Anesthesia, Analgesia and Critical CareParvalbumin-positive (PV+) interneurons (basket and chandelier cells) regulate the firing rate of pyramidal neurons in the cerebral cortex and play a key role in the generation of network oscillations in the cerebral cortex.
Giada Mascio +3 more
doaj +1 more source