Results 1 to 10 of about 158 (88)
Cell Reports, 2021 Summary: The mediobasal hypothalamus (MBH; arcuate nucleus of the hypothalamus [ARH] and median eminence [ME]) is a key nutrient sensing site for the production of the complex homeostatic feedback responses required for the maintenance of energy balance.
Sophie Buller +2 more
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Neural Regeneration Research, 2022 Damage to the vestibular sense organs evokes static and dynamic deficits in the eye movements, posture and vegetative functions. After a shorter or longer period of time, the vestibular function is partially or completely restored via a series of ...
Agnes Magyar +5 more
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Perineuronal Net Receptor PTPσ Regulates Retention of Memories
Frontiers in Synaptic Neuroscience, 2021 Perineuronal nets (PNNs) have an important physiological role in the retention of learning by restricting cognitive flexibility. Their deposition peaks after developmental periods of intensive learning, usually in late childhood, and they help in long ...
Angelina Lesnikova +5 more
doaj +1 more source
Neonatal Zika virus infection causes transient perineuronal net degradation
Frontiers in Cellular Neuroscience, 2023 Perineuronal nets (PNNs) form a specialized extracellular matrix that predominantly surrounds parvalbumin (PV)-expressing GABAergic inhibitory interneurons and help regulate neuronal activity. Their formation early in the postnatal period is regulated by
Kaliroi Engel +6 more
doaj +1 more source
Beta3Gn-T7 Is a Keratan Sulfate β1,3 N-Acetylglucosaminyltransferase in the Adult Brain
Frontiers in Neuroanatomy, 2022 Keratan sulfate (KS) glycan is covalently attached to a core protein of proteoglycans. KS is abundant in neuropils and presents densely in close proximity to the perineuronal region of the perineuronal net-positive neurons in the adult brain under ...
Yoshiko Takeda-Uchimura +6 more
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Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure
BMC Biology, 2022 Background Perineuronal nets (PNNs) are specialized extracellular matrix structures mainly found around fast-spiking parvalbumin (FS-PV) interneurons. In the adult, their degradation alters FS-PV-driven functions, such as brain plasticity and memory, and
Matthieu Lépine +15 more
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Parvalbumin interneuron alterations in stress-related mood disorders: A systematic review
Neurobiology of Stress, 2021 Stress-related psychiatric disorders including depression involve complex cellular and molecular changes in the brain, and GABAergic signaling dysfunction is increasingly implicated in the etiology of mood disorders.
George Perlman +2 more
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Experience-dependent plasticity and modulation of growth regulatory molecules at central synapses. [PDF]
PLoS ONE, 2011 Structural remodeling or repair of neural circuits depends on the balance between intrinsic neuronal properties and regulatory cues present in the surrounding microenvironment.
Simona Foscarin +7 more
doaj +1 more source
The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders
Frontiers in Molecular Neuroscience, 2018 Perineuronal nets (PNN) are extracellular matrix (ECM) assemblies that preferentially ensheath parvalbumin (PV) expressing interneurons. Converging evidence indicates that PV cells and PNN are impaired in a variety of neurological disorders.
Teresa H. Wen +6 more
doaj +1 more source
Update on Perineuronal Net Staining With Wisteria floribunda Agglutinin (WFA)
Frontiers in Integrative Neuroscience, 2022 As chemically specialized forms of the extracellular matrix in the central nervous system, polyanionic perineuronal nets (PNs) contain diverse constituents, including chondroitin sulfate proteoglycans (CSPGs), hyaluronic acid, and tenascins.
Wolfgang Härtig +5 more
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