Results 41 to 50 of about 1,848 (164)
Perineuronal nets stabilize the grid cell network [PDF]
Nature Communications, 2019 Abstract Grid cells are part of a widespread network that supports navigation and spatial memory. Stable grid patterns appear late in development, in concert with extracellular matrix aggregates termed perineuronal nets (PNNs) that condense around inhibitory neurons.
Ane Charlotte Christensen +7 more
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Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties
Cell Reports, 2019 Summary: Dendritic spines control synaptic transmission and plasticity by augmenting post-synaptic potentials and providing biochemical compartmentalization.
Angelica Foggetti +4 more
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Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity [PDF]
The Journal of Neuroscience, 2016 Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain neurons in the CNS during development and control plasticity in the adult CNS. They appear to contribute to a wide range of diseases/disorders of the brain, are involved in recovery from spinal cord injury, and are altered during aging, learning and memory, and
Sorg, Barbara A +6 more
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BiologyEvidence is strong that, in addition to fine motor control, there is an important role for the cerebellum in cognition and emotion. The deep nuclei of the mammalian cerebellum also contain the highest density of perineural nets—mesh-like structures that ...
Bernard G. Schreurs +2 more
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Cell Reports, 2019 Summary: Adolescence is a vulnerable period characterized by major cognitive changes. The mechanisms underlying the emergence of new cognitive functions are poorly understood.
Soledad Domínguez +7 more
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Comparative analysis of the methods for quantitative study of the perineuronal net microstructure
Учёные записки Казанского университета: Серия Естественные науки, 2022 Perineuronal nets (PNN) are a special and highly structured type of the CNS extracellular matrix. In past few years, the important role of PNN in the normal physiology of the CNS and the changes in their expression associated with some pathologies have ...
N.S. Lipachev +4 more
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Perineuronal Nets: Subtle Structures with Large Implications
The Neuroscientist, 2022 Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround the soma and proximal dendrites of certain neurons in the central nervous system, particularly parvalbumin-expressing interneurons. Their appearance overlaps the maturation of neuronal circuits and the closure of critical periods in different regions of the ...
Héctor Carceller +3 more
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Biomolecules, 2020 The chondroitin sulfate (CS)-rich dense extracellular matrix surrounding neuron cell bodies and proximal dendrites in a mesh-like structure is called a perineuronal net (PNN).
Satomi Nadanaka +5 more
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WFA-labeled perineuronal nets in the macaque claustrum [PDF]
Claustrum, 2018 The claustrum (CLA) has been discussed as central to integrated conscious percepts, although recent evidence has emphasized a role in detecting sensory novelty or in amplifying correlated cortical inputs.We report that many neurons in the macaque CLA are ensheathed in perineuronal nets (PNNs), which contribute to synaptic stability and enhance neuronal
Mihovil Pletikos, Kathleen S. Rockland
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Frontiers in NeuroanatomyNormal brain development requires continuous communication between developing neurons and their environment filled by a complex network referred to as extracellular matrix (ECM). The ECM is divided into distinct families of molecules including hyaluronic
Ildikó Wéber +5 more
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