Results 61 to 70 of about 158 (88)

Juvenile stress induces behavioral change and affects perineuronal net formation in juvenile mice

BMC Neuroscience, 2018
Background Many neuropsychiatric disorders develop in early life. Although the mechanisms involved have not been elucidated, it is possible that functional abnormalities of parvalbumin-positive interneurons (PV neurons) are present.
Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Shozo Aoki, Takeshi Ishihara   +8 more
doaj   +1 more source

Understanding neurodegeneration and regeneration in the CNS: New concepts, clinical investigations, and an unsung hero of neuroscience

Neuroprotection, Volume 4, Issue 3, Page 191-194, September 2026.
Piotr Walczak, Shen Li, Xunming Ji, Johannes Boltze   +3 more
wiley   +1 more source

Right medial temporal lobe mass in a 25‐year‐old male

Brain Pathology, Volume 36, Issue 5, September 2026.
Jorge Samanamud, Cheyanne C. Slocum, Michael Christian Virata, Zied Abdullaev, Kenneth Aldape, Melissa Umphlett, Raymund L. Yong, Thomas P. Naidich, Nadejda M. Tsankova, Jamie M. Walker, Timothy E. Richardson   +10 more
wiley   +1 more source

Electroacupuncture facilitates remote fear memory erasure via promoting perineuronal net degradation

Translational Psychiatry
Post-retrieval extinction has been effective in erasing recent pathological memories but has been shown failed in erasing remote memories. Pathological memories are often formed over the long term, therefore how to erase the remote pathological memory ...
Shuai-Wen Teng, Wen-Bo Guo, Bing-Feng Song, Yun-Zhang He, Ke-Yan Wang, Shi-Bin Gao, Wei Li, Zhe-Yu Chen   +7 more
doaj   +1 more source

Assessing translational applicability of perineuronal net dysfunction in Alzheimer’s disease across species

Frontiers in Neuroscience
In the context of aging and age-associated neurodegenerative disorders, the brain’s extracellular matrix (ECM) serves as a critical regulator for neuronal health and cognitive function.
Aarun S. Hendrickson, Aarun S. Hendrickson, Kendra L. Francis, Kendra L. Francis, Asmit Kumar, Asmit Kumar, Jaden P. Le, Jaden P. Le, Jarrad M. Scarlett, Jarrad M. Scarlett, C. Dirk Keene, David A. Tovar, Kimberly M. Alonge, Kimberly M. Alonge   +13 more
doaj   +1 more source

Developmental CA2 perineuronal net reduction restores social memory in Shank3 mutant mice

Communications Biology
Individuals with Autism Spectrum Disorder (ASD) and related neurodevelopmental conditions, like Phelan-McDermid syndrome (PMDS), exhibit social recognition deficits.
Emma J. Diethorn, Aarushi B. Rathaur, Brayan R. Ruiz Lopez, Chino K. Eke, Elizabeth Gould   +4 more
doaj   +1 more source

Reorganization of Synaptic Connections and Perineuronal Nets in the Deep Cerebellar Nuclei of Purkinje Cell Degeneration Mutant Mice

Neural Plasticity, 2016
The perineuronal net (PN) is a subtype of extracellular matrix appearing as a net-like structure around distinct neurons throughout the whole CNS. PNs surround the soma, proximal dendrites, and the axonal initial segment embedding synaptic terminals on ...
M. Blosa, C. Bursch, S. Weigel, M. Holzer, C. Jäger, C. Janke, R. T. Matthews, T. Arendt, M. Morawski   +8 more
doaj   +1 more source

Reorganization of Spinal Cord Microarchitecture by Bioluminescent Optogenetic and Rehabilitative Interventions

Cells
Spinal cord injury (SCI) induces persistent locomotor deficits that are closely associated with maladaptive structural plasticity of spinal neuronal circuits.
Tatyana Ageeva, Rezeda Shigapova, Aizilya Bilalova, Elizaveta Plotnikova, Amina Akmanova, Albert Rizvanov, Yana Mukhamedshina   +6 more
doaj   +1 more source

How the forebrain transitions to adulthood: developmental plasticity markers in a long-lived rodent reveal region diversity and the uniqueness of adolescence

Frontiers in Neuroscience
Maturation of the forebrain involves transitions from higher to lower levels of synaptic plasticity. The timecourse of these changes likely differs between regions, with the stabilization of some networks scaffolding the development of others.
B. Maximiliano Garduño, Patrick Hanni, Chelsea Hays, Patricia Cogram, Patricia Cogram, Nathan Insel, Nathan Insel, Xiangmin Xu, Xiangmin Xu, Xiangmin Xu   +9 more
doaj   +1 more source

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An Extracellular Perspective on CNS Maturation: Perineuronal Nets and the Control of Plasticity

International Journal of Molecular Sciences, 2021
Joost Verhaagen, Daniela Carulli
exaly