Results 81 to 90 of about 1,903 (160)

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Juvenile stress induces behavioral change and affects perineuronal net formation in juvenile mice

BMC Neuroscience, 2018
Background Many neuropsychiatric disorders develop in early life. Although the mechanisms involved have not been elucidated, it is possible that functional abnormalities of parvalbumin-positive interneurons (PV neurons) are present.
Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Shozo Aoki, Takeshi Ishihara   +8 more
doaj   +1 more source

Right medial temporal lobe mass in a 25‐year‐old male

Brain Pathology, Volume 36, Issue 5, September 2026.
Jorge Samanamud, Cheyanne C. Slocum, Michael Christian Virata, Zied Abdullaev, Kenneth Aldape, Melissa Umphlett, Raymund L. Yong, Thomas P. Naidich, Nadejda M. Tsankova, Jamie M. Walker, Timothy E. Richardson   +10 more
wiley   +1 more source

Effect of Shock-Induced Cavitation Bubble Collapse on the damage in the Simulated Perineuronal Net of the Brain

Scientific Reports, 2017
The purpose of this study is to conduct modeling and simulation to understand the effect of shock-induced mechanical loading, in the form of cavitation bubble collapse, on damage to the brain’s perineuronal nets (PNNs).
Yuan-Ting Wu, Ashfaq Adnan
doaj   +1 more source

Neurocan Inhibits Semaphorin 3F Induced Dendritic Spine Remodeling Through NrCAM in Cortical Neurons

Frontiers in Cellular Neuroscience, 2018
Neurocan is a chondroitin sulfate proteoglycan present in perineuronal nets, which are associated with closure of the critical period of synaptic plasticity.
Vishwa Mohan, Elliott V. Wyatt, Ingo Gotthard, Kristen D. Phend, Simone Diestel, Bryce W. Duncan, Richard J. Weinberg, Ashutosh Tripathy, Patricia F. Maness   +8 more
doaj   +1 more source

Chondroitin Sulfate Expression in Perineuronal Nets After Goldfish Spinal Cord Lesion

Frontiers in Cellular Neuroscience, 2018
Perineuronal nets (PNNs) surrounding neuronal cell bodies regulate neuronal plasticity during development, but their roles in regeneration are unclear. In the PNNs, chondroitin sulfate (CS) is assumed to be involved in inhibiting contact formation. Here,
Akihito Takeda, Masashige Shuto, Kengo Funakoshi   +2 more
doaj   +1 more source

Reorganization of Synaptic Connections and Perineuronal Nets in the Deep Cerebellar Nuclei of Purkinje Cell Degeneration Mutant Mice

Neural Plasticity, 2016
The perineuronal net (PN) is a subtype of extracellular matrix appearing as a net-like structure around distinct neurons throughout the whole CNS. PNs surround the soma, proximal dendrites, and the axonal initial segment embedding synaptic terminals on ...
M. Blosa, C. Bursch, S. Weigel, M. Holzer, C. Jäger, C. Janke, R. T. Matthews, T. Arendt, M. Morawski   +8 more
doaj   +1 more source

Reorganization of Spinal Cord Microarchitecture by Bioluminescent Optogenetic and Rehabilitative Interventions

Cells
Spinal cord injury (SCI) induces persistent locomotor deficits that are closely associated with maladaptive structural plasticity of spinal neuronal circuits.
Tatyana Ageeva, Rezeda Shigapova, Aizilya Bilalova, Elizaveta Plotnikova, Amina Akmanova, Albert Rizvanov, Yana Mukhamedshina   +6 more
doaj   +1 more source

Perineuronal nets in neurodegeneration

Oncotarget, 2016
Lemarchant, Sighild, Wojciechowski, Sara, Koistinaho, Jari   +2 more
openaire   +2 more sources

The omics techniques used in perineuronal nets research

Experimental Neurology
Neurodegenerative diseases (NDs) are progressive disorders characterized by neuronal degeneration in the central nervous system (CNS), ultimately leading to neurological dysfunction. Neurodegenerative progression is often associated with structural and functional alterations in perineuronal nets (PNNs).
Sihan, Huang, Jiao, Tang, Xiao, Wu, Huan, Xu, Sihui, Li, Hongying, Li, Siyu, Zhang, Guangxin, Xie, Tingyu, Wang, Xincheng, Pan, Ahmad, Fasih, Maochun, You, Zhanqiong, Zhong, Lushuang, Xie, Qiaofeng, Wu, Shuguang, Yu   +15 more
openaire   +2 more sources