Results 31 to 40 of about 2,231 (191)
Experience-dependent plasticity and modulation of growth regulatory molecules at central synapses. [PDF]
PLoS ONE, 2011 Structural remodeling or repair of neural circuits depends on the balance between intrinsic neuronal properties and regulatory cues present in the surrounding microenvironment.
Simona Foscarin +7 more
doaj +1 more source
Hippocampal perineuronal net degradation identifies prefrontal and striatal circuits involved in schizophrenia-like changes in marmosets. [PDF]
Sci AdvIn schizophrenia, anterior hippocampus (aHipp) overactivity is associated with orbitofrontal cortex (OFC) dysfunction, but the contribution to symptomatology is unknown.
Gwilt MA +15 more
europepmc +2 more sources
Scientific Reports, 2022 Postnatal hippocampal neurogenesis has been demonstrated to affect learning and memory in numerous ways. Several studies have now demonstrated that increased neurogenesis can induce forgetting of memories acquired prior to the manipulation of ...
Alexandria Evans +4 more
doaj +1 more source
Frontiers in Neuroanatomy, 2019 Environmental enrichment can dramatically affect both the development and function of neural circuits. This is accomplished, at least in part, by the regulation of inhibitory cellular networks and related extracellular matrix glycoprotein structures ...
Angela May O’Connor +5 more
doaj +1 more source
Biomolecules, 2021 Because of their abilities to catalyze generation of toxic free radical species, free concentrations of the redox reactive metals iron and copper are highly regulated.
Jessica A. Burket +2 more
doaj +1 more source
Perineuronal nets: Cruise from a honeycomb to the safety nets
Brain Research Bulletin, 2022 The extracellular matrix (ECM) is a significant component of the brain, constituting up to 20 % of the brain volume and perform multifarious functions during development, maturation and regeneration of the central nervous system (CNS). ECM molecules assemble systematically to form a relatively rigid and unique lattice-like structure, known as ...
Urmilla John, Nisha Patro, Ishan Patro
openaire +2 more sources
Proteoglycan Sulphation in the Function of the Mature Central Nervous System
Frontiers in Integrative Neuroscience, 2022 Chondroitin sulphate and heparan sulphate proteoglycans (CSPGS and HSPGs) are found throughout the central nervous system (CNS). CSPGs are ubiquitous in the diffuse extracellular matrix (ECM) between cells and are a major component of perineuronal nets ...
James W. Fawcett +3 more
doaj +1 more source
Perineuronal Nets and CNS Plasticity and Repair [PDF]
Neural Plasticity, 2016 The extracellular matrix (ECM) of the nervous system regulates numerous events during development, from neurogenesis and gliogenesis to circuitry formation, as well as in adulthood, affecting damage responses, plasticity, and regeneration. Substantial changes in the quantity and the composition of ECM occur during development.
Carulli, Daniela +2 more
openaire +6 more sources
Diverse functions of perineuronal nets
Acta Neurobiologiae Experimentalis, 2009 Perineuronal nets represent well-organised components of the extracellular matrix, which are surrounding cell bodies, dendrites, and axon segments of a particular class of neurones as well as forming lattice-like structures. The role of perineuronal nets is not fully elucidated yet.
Magdalena, Karetko +1 more
openaire +2 more sources
Longitudinal in vivo imaging of perineuronal nets
Neurophotonics, 2023 Perineuronal nets (PNNs) are extracellular matrix structures implicated in learning, memory, information processing, synaptic plasticity, and neuroprotection. However, our understanding of mechanisms governing the evidently important contribution of PNNs to central nervous system function is lacking.
Benbenishty, Amit +8 more
openaire +2 more sources