Results 121 to 130 of about 3,965 (209)

The omics techniques used in perineuronal nets research

Experimental Neurology
Neurodegenerative diseases (NDs) are progressive disorders characterized by neuronal degeneration in the central nervous system (CNS), ultimately leading to neurological dysfunction. Neurodegenerative progression is often associated with structural and functional alterations in perineuronal nets (PNNs).
Sihan, Huang, Jiao, Tang, Xiao, Wu, Huan, Xu, Sihui, Li, Hongying, Li, Siyu, Zhang, Guangxin, Xie, Tingyu, Wang, Xincheng, Pan, Ahmad, Fasih, Maochun, You, Zhanqiong, Zhong, Lushuang, Xie, Qiaofeng, Wu, Shuguang, Yu   +15 more
openaire   +2 more sources

Removal of perineuronal nets disrupts recall of a remote fear memory

, 2017
Significance Perineuronal nets (PNNs), a type of extracellular matrix only found in the central nervous system, wraps tightly around the cell soma and proximal dendrites of a subset of neurons. The PNNs are long-lasting structures that restrict
Kristian Kinden Lensjø, Marianne Fyhn, Mattis Brænne Wigestrand, Torkel Hafting, Anders Malthe-Sørenssen, Elise Holter Thompson   +5 more
core   +1 more source

Mossy Fibers from Adult-generated Neurons in the Dentate Gyrus More Frequently Contact Hilar Interneurons Surrounded by Intense Perineuronal Nets

, 2019
In the present study, we aimed to research whether there was any significant relationship between hippocampal adult-born neurons’ maturation and perineuronal nets in the dorsal hippocampus.
Haye, Amanda
core  

A type-5 metabotropic glutamate receptor-perineuronal net axis shapes the function of cortical GABAergic interneurons in chronic pain

Journal of Anesthesia, Analgesia and Critical Care
Parvalbumin-positive (PV+) interneurons (basket and chandelier cells) regulate the firing rate of pyramidal neurons in the cerebral cortex and play a key role in the generation of network oscillations in the cerebral cortex.
Giada Mascio, Ferdinando Nicoletti, Giuseppe Battaglia, Serena Notartomaso   +3 more
doaj   +1 more source

Modulation of memory using enzymatic digestion of perineuronal nets in perirhinal cortex

, 2019
In the adult brain, neuronal plasticity is regulated by a specialized structure of extracellular matrix, the perineuronal nets (PNNs), which restrict synaptic plasticity by binding molecules of inhibitory nature and posing as a physical barrier to ...
Procházková, Natálie
core  

CDKL5 deficiency results in atypical subregion-specific expression of perineuronal nets during mouse visual critical period. [PDF]

Front Neurosci
Emery BA, Everett M, Dunn LR, Lau BYB, Krishnan K.   +4 more
europepmc   +1 more source

Adolescent cannabinoid exposure delays development of prefrontal cortex perineuronal nets and inhibitory interneurons. [PDF]

Neuroscience
Jacobs-Brichford E, Donka RM, Lasek AW, Hsu TM, Roitman JD.   +4 more
europepmc   +1 more source

Editorial: Perineuronal Nets as Therapeutic Targets for the Treatment of Neuropsychiatric Disorders

Dysregulated synaptic plasticity and excitatory inhibitory (E/I) imbalance are molecular hallmarks of multiple neuropsychiatric disorders. Perineuronal nets (PNNs) are condensed portions of the extracellular matrix (ECM) that stabilize homeostatic ...
Lasek, Amy W., Nácher Roselló, Juan Salvador, Browne, Caroline A., Conant, Katherine   +3 more
core   +1 more source

Perineuronal nets in cerebellar nuclei neurons orchestrate social behaviour via regulation of neuronal activity in circuits innervated by the cerebellum. [PDF]

Transl Psychiatry
Fujita K, Zhu H, Tsuji C, Kawamura A, Nishiyama M, Higashida H, Yokoyama S.   +6 more
europepmc   +1 more source

Characterization of Perineuronal Nets in the Paraventricular Nucleus of the Hypothalamus and their Alteration in Neurogenic Hypertension. [PDF]

Cell Mol Neurobiol
Blanco I, Chen S, Yeo E, Reasonover S, Santisteban MM.   +4 more
europepmc   +1 more source