Results 181 to 190 of about 5,932 (219)
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The Perineuronal Net: A Weapon for a Challenge
Journal of the History of the Neurosciences, 1999Theories and data do not always fit and sometimes are sources of conflicts among scientists. This is the case of a morphological structure, the perineuronal net, which was denied on the basis of an ideological conflict between two giants of neurosciences: Camillo Golgi and Santiago Ramon y Cajal. The perineuronal net is a reticular structure enveloping
R, Spreafico +2 more
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Perineuronal nets in the auditory system
Hearing Research, 2015Perineuronal nets (PNs) are a unique and complex meshwork of specific extracellular matrix molecules that ensheath a subset of neurons in many regions of the central nervous system (CNS). PNs appear late in development and are supposed to restrict synaptic plasticity and to stabilize functional neuronal connections.
Mandy, Sonntag +4 more
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Neurocan Contributes to Perineuronal Net Development
Neuroscience, 2020Perineuronal nets (PNs) are matrix molecule assemblies surrounding neuronal somata, dendrites and axon initial segments in a lattice-like appearance. PN molecules are involved in many structural and physiological processes during development and in adulthood, suggesting a crucial role in normal brain function.
Sophie, Schmidt +3 more
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Perineuronal nets: past and present
Trends in Neurosciences, 1998Golgi ranked the peripheral reticulum--which adheres intimately to nerve cell surfaces--alongside the intracellular reticulum, or Golgi apparatus,which immortalized his name. At first dismissed as an artefact of capricious staining techniques, this peripheral reticulum, or perineuronal net, is now recognized as a genuine entity in neurocytology.
Celio MR +3 more
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Perineuronal nets and schizophrenia: The importance of neuronal coatings [PDF]
Neuroscience and Biobehavioral Reviews, 2014 Schizophrenia is a complex brain disorder associated with deficits in synaptic connectivity. The insidious onset of this illness during late adolescence and early adulthood has been reported to be dependent on several key processes of brain development including synaptic refinement, myelination and the physiological maturation of inhibitory neural ...
Tsung-Ung W Woo
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The two faces of perineuronal nets
NeuroReport, 2000Perineuronal nets are extracellular structures enwrapping the soma and proximal dendrites of some neurons known to be parvalbumin immunoreactive. The composition of the nets is not completely known, but it can change between different neurons. We studied the heterogeneous composition of a specific component of perineuronal nets, the signaling molecule ...
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Perineuronal nets’ role in metabolism
American Journal of Physiology-Endocrinology and MetabolismPerineuronal nets (PNNs), specialized extracellular matrix (ECM) structures that envelop neurons, have recently been recognized as key players in the regulation of metabolism. This review explores the growing body of knowledge concerning PNNs and their role in metabolic control, drawing insights from recent research and relevant studies.
Nan Zhang +6 more
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The perineuronal net and the control of CNS plasticity
Cell and Tissue Research, 2012Perineuronal nets (PNNs) are reticular structures that surround the cell body of many neurones, and extend along their dendrites. They are considered to be a specialized extracellular matrix in the central nervous system (CNS). PNN formation is first detected relatively late in development, as the mature synaptic circuitry of the CNS is established and
Difei, Wang, James, Fawcett
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Journal fur Hirnforschung, 1983
Perineuronal nets could be visualized with some Golgi methods in the rat's brain. Nets were seen in telencephalic, diencephalic and mesencephalic structures covering somata and proximal dendrites of different neuronal types. Some nets could be found originating from microglia cells. In most cases their origin is not recognizable.
K, Brauer, L, Werner, L, Leibnitz
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Perineuronal nets could be visualized with some Golgi methods in the rat's brain. Nets were seen in telencephalic, diencephalic and mesencephalic structures covering somata and proximal dendrites of different neuronal types. Some nets could be found originating from microglia cells. In most cases their origin is not recognizable.
K, Brauer, L, Werner, L, Leibnitz
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Characterization of Perineuronal Nets in the Human Cerebellum
The CerebellumPerineuronal nets (PNNs) are condensed extracellular matrix structures that regulate synaptic plasticity and neuronal stability. While their distribution and function have been well characterized in rodents, PNNs remain largely understudied in the human cerebellum.
Refilwe, Mpai +9 more
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