Results 171 to 180 of about 3,965 (209)

Differential Impact of Adolescent or Adult Stress on Behavior and Cortical Parvalbumin Interneurons and Perineuronal Nets in Male and Female Mice. [PDF]

open access: yesInt J Neuropsychopharmacol
Santos-Silva T   +6 more
europepmc   +1 more source

Perineuronal Nets: Plasticity, Protection, and Therapeutic Potential

open access: yesTrends in Neurosciences, 2019
© 2019 Elsevier Ltd The relationship between neurons and perineuronal nets (PNNs) is attracting attention as a central mechanism controlling brain plasticity.
Amy C Reichelt   +2 more
exaly   +6 more sources

An Extracellular Perspective on CNS Maturation: Perineuronal Nets and the Control of Plasticity [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
During restricted time windows of postnatal life, called critical periods, neural circuits are highly plastic and are shaped by environmental stimuli. In several mammalian brain areas, from the cerebral cortex to the hippocampus and amygdala, the closure
Daniela Carulli   +2 more
exaly   +2 more sources

Temporal and spatial appearance of the membrane cytoskeleton and perineuronal nets in the rat neocortex

open access: yesNeuroscience Letters, 1996
Parvalbumin-immunoreactive interneurons are surrounded by perineuronal nets, containing molecules of the extracellular matrix (e.g. tenascin-R). Furthermore, they seem to have a special cytoskeleton composed of, among others, ankyrinR and beta Rspectrin.
Beat M Riederer   +2 more
exaly   +2 more sources

Releasing Addiction Memories Trapped in Perineuronal Nets [PDF]

open access: yesTrends in Genetics, 2018
Drug addiction can be conceptualized at a basic level as maladaptive learning and memory. Addictive substances elicit changes in brain circuitry involved in reward, cognition, and emotional state, leading to the formation and persistence of strong drug-associated memories that lead to craving and relapse.
Amy W Lasek, Wei-Yang Chen
exaly   +3 more sources

The Perineuronal Net: A Weapon for a Challenge

Journal of the History of the Neurosciences, 1999
Theories and data do not always fit and sometimes are sources of conflicts among scientists. This is the case of a morphological structure, the perineuronal net, which was denied on the basis of an ideological conflict between two giants of neurosciences: Camillo Golgi and Santiago Ramon y Cajal. The perineuronal net is a reticular structure enveloping
R, Spreafico   +2 more
openaire   +2 more sources

Perineuronal nets in the auditory system

Hearing Research, 2015
Perineuronal nets (PNs) are a unique and complex meshwork of specific extracellular matrix molecules that ensheath a subset of neurons in many regions of the central nervous system (CNS). PNs appear late in development and are supposed to restrict synaptic plasticity and to stabilize functional neuronal connections.
Mandy, Sonntag   +4 more
openaire   +2 more sources

Neurocan Contributes to Perineuronal Net Development

Neuroscience, 2020
Perineuronal nets (PNs) are matrix molecule assemblies surrounding neuronal somata, dendrites and axon initial segments in a lattice-like appearance. PN molecules are involved in many structural and physiological processes during development and in adulthood, suggesting a crucial role in normal brain function.
Sophie, Schmidt   +3 more
openaire   +2 more sources

Perineuronal nets: past and present

Trends in Neurosciences, 1998
Golgi ranked the peripheral reticulum--which adheres intimately to nerve cell surfaces--alongside the intracellular reticulum, or Golgi apparatus,which immortalized his name. At first dismissed as an artefact of capricious staining techniques, this peripheral reticulum, or perineuronal net, is now recognized as a genuine entity in neurocytology.
Celio MR   +3 more
openaire   +3 more sources

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