Results 241 to 250 of about 43,915 (298)

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets. [PDF]

FEBS Lett
Brinckman ED, Lester AE, Zoltowski BD.
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Advances in research on circadian rhythms and colorectal cancer. [PDF]

BMC Med Genomics
Jia L, Zhu M, Wu X, Zheng W, Zhang Y, Xiao J.   +5 more
europepmc   +1 more source

Seven days of warm‐water immersion enhances resting irisin and BDNF, but not klotho, in older men

Experimental Physiology, EarlyView.
Abstract We examined whether seven consecutive days of warm‐water immersion could elevate resting and exercise‐induced levels of brain‐derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and metabolic health, but their levels decline with age.
Joel M Garrett, James J McCormick, Kelli E King, Kristina‐Marie T Janetos, Nathalie V Kirby, Fergus K O'Connor, Glen P Kenny   +6 more
wiley   +1 more source

Indication of diurnal variations in the rat choroid plexus for cerebrospinal fluid secretion. [PDF]

Biochem Biophys Rep
Yamaguchi T, Hamada T, Matsuzaki T, Iijima N.   +3 more
europepmc   +1 more source

Effect of repeated hot water immersion on cognitive performance, cerebrovascular function, sleep and biomarkers of neurodegeneration in older adults

Experimental Physiology, EarlyView.
Abstract Ageing is associated with cognitive decline and increased risk of developing neurodegenerative disease. Repeated passive heating, using hot water immersion (HWI), may improve cognitive performance via improved cerebral oxygenation, but this is yet to be examined in older adults.
Daniel D. Piccolo, Jo Corbett, Joseph T. Costello, Thomas B. Williams, Thomas J. James, Janis K. Shute, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Harry S. Mayes, Michael Tipton, Maria Perissiou, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +16 more
wiley   +1 more source

Quantifying skin microvascular function responses to distinct forms of heat stress in humans using optical coherence tomography

Experimental Physiology, EarlyView.
Abstract Optical coherence tomography (OCT) enables visualization and quantification of the cutaneous microvasculature, yet no study has compared responses to distinct forms of heating in humans. We hypothesized that local skin heating (LH) would evoke larger responses in microvascular diameter, velocity, flow and density than passive whole‐body ...
Kristanti W. Wigati, Robert A. McLaughlin, Harrison T. Caddy, Howard H. Carter, Louise H. Naylor, Daniel J. Green   +5 more
wiley   +1 more source

Jumping in simulated lunar gravity with blood flow restriction as a potential exercise countermeasure: The acute physiological effects

Experimental Physiology, EarlyView.
Abstract The present study examined the cardiovascular, metabolic, neuromuscular and perceptual effects of low‐intensity jumping in simulated lunar gravity (∼20% bodyweight) with blood flow restriction (BFR). Fourteen healthy adults (24 ± 4 years; 1.81 ± 0.06 m; 75 ± 12 kg) completed an incremental jumping test in simulated lunar gravity (9.5° head‐up ...
Patrick Swain, Filipa Santos, Nick Caplan, Cody Latue, Billie Illingworth, Nicky Sheard, Luke Hughes   +6 more
wiley   +1 more source

The Cardiac Circadian Clock Regulates Rhythms in Peripheral Tissues via Fibulin 5. [PDF]

Compr Physiol
Bettadapura SS, Tangeman DC, Satyanarayana SB, Ruhmann MM, Bonds WJ, Edwards JH, Gupta P, Yusifov A, Todd WD, Bruns DR.   +9 more
europepmc   +1 more source