Results 31 to 40 of about 38,595 (241)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

The mechanical environment modulates intracellular calcium oscillation activities of myofibroblasts. [PDF]

PLoS ONE, 2013
Myofibroblast contraction is fundamental in the excessive tissue remodeling that is characteristic of fibrotic tissue contractures. Tissue remodeling during development of fibrosis leads to gradually increasing stiffness of the extracellular matrix.
Charles Godbout, Lysianne Follonier Castella, Eric A Smith, Nilesh Talele, Melissa L Chow, Adriano Garonna, Boris Hinz   +6 more
doaj   +1 more source

Topological and Mechanical Properties of Different Lattice Structures Based on Additive Manufacturing

Micromachines, 2022
The appearance and development of additive manufacturing technology promotes the production and manufacture of parts with more complex designs and smaller sizes and realizes the complex topology that cannot be made by equal-material manufacturing and ...
Fei Teng, Yongguo Sun, Shuai Guo, Bingwei Gao, Guangbin Yu   +4 more
doaj   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

A theoretical method to analyze the effect of stress distribution on compressive strength of periodic lattices

Materials & Design
The lattice structures or lattice metamaterials have been widely used in aerospace and medical fields, and the mechanical properties were mostly evaluated based on simulated stress distribution.
Zulei Liang, Yansong Meng, Jiaxi Zhao, Zhanggang Sun, Yanhua Guo, Jie Xia, Hui Chang, Lian Zhou, I.V. Alexandrov   +8 more
doaj   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Comportamento dinâmico-mecânico e relaxações em polímeros e blendas poliméricas Dynamic mechanical behavior and relaxations in polymers and polymeric blends

Química Nova, 2005
Dynamic mechanical analysis (DMA) is widely used in materials characterization. In this work, we briefly introduce the main concepts related to this technique such as, linear and non-linear viscoelasticity, relaxation time, response of material when it ...
Silvana Navarro Cassu, Maria Isabel Felisberti   +1 more
doaj   +1 more source

Lattice structures of Cu-Cr-Zr copper alloy by selective laser melting: Microstructures, mechanical properties and energy absorption

Materials & Design, 2020
Characterized by high thermal-electrical conductivity and reasonable specific strength, lattice structures of copper alloy have great potential in industrial applications.
Zhibo Ma, David Z. Zhang, Fei Liu, Junjie Jiang, Miao Zhao, Tao Zhang   +5 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source