Results 51 to 60 of about 38,595 (241)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Mechanical properties of AlSi10Mg lattice structures fabricated by selective laser melting

Materials & Design, 2020
Al alloy porous structures have potential application in industries such as light aerospace and some heat exchanger products. A particular advantage of selective laser melting (SLM) over conventional manufacturing processes is its ability to fabricate ...
Zhong-hua Li, Yun-fei Nie, Bin Liu, Ze-zhou Kuai, Miao Zhao, Fei Liu   +5 more
doaj   +1 more source

Effects of Automatic Thoughts and Coping With Stress Mechanisms on Intolerance to Uncertainty in Adult Period

Psikiyatride Güncel Yaklaşımlar, 2021
The aim of this study was to determine the relationships between coping with stress, intolerance to uncertainty and automatic thoughts. The research sample consists of 393 (Male: 194, Female: 199) volunteer participants living in Central Anatolia. The research data were collected using the Stress Coping Styles Scale, Intolerance to Uncertainty Scale ...
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Influence of deformed primitive architecture on mechanical behavior of artificial porous meniscus

Materials & Design, 2020
Polycarbonate urethane (PCU) has emerged as a suitable material for artificial meniscus replacement after meniscectomy. However, the commercial PCU meniscal replacements could not reproduce native meniscus performance until now. The aim of this paper was
Li-ya Zhu, Ming Cheng, Wen-chen Sun, Ji-quan Yang, Lan Li, Qing Jiang   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Numerical investigation of the mechanical properties of lattice structures inspired from polycrystalline materials

AIP Advances
In this work, polycrystalline-like lattice structures that are inspired by the geometry of polycrystalline materials are designed. They are generated by filling periodic lattice structures into a Voronoi diagram.
Yabo Liu, Guangwei Bai, Zhipeng Qu, Xiaochang Xu   +3 more
doaj   +1 more source

Stress strain curve analysis of sheet based TPMS structures in quasi static compression test: A review

Journal of Materials Research and Technology
Stress-strain behaviour of Triply Periodic Minimal Surface (TPMS) structures presents challenges in predicting their mechanical properties. Current studies are hindered by limitations in modelling its complex geometries.
Izzat Mat Samudin, Nabilah Afiqah Mohd Radzuan, Abu Bakar Sulong, Quanjin Ma, Abdul Hadi Azman, Wan Fathul Hakim Wan Zamri   +5 more
doaj   +1 more source