Results 51 to 60 of about 246,063 (270)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A theoretical method to analyze the effect of stress distribution on compressive strength of periodic lattices

Materials & Design
The lattice structures or lattice metamaterials have been widely used in aerospace and medical fields, and the mechanical properties were mostly evaluated based on simulated stress distribution.
Zulei Liang, Yansong Meng, Jiaxi Zhao, Zhanggang Sun, Yanhua Guo, Jie Xia, Hui Chang, Lian Zhou, I.V. Alexandrov   +8 more
doaj   +1 more source

Comportamento dinâmico-mecânico e relaxações em polímeros e blendas poliméricas Dynamic mechanical behavior and relaxations in polymers and polymeric blends

Química Nova, 2005
Dynamic mechanical analysis (DMA) is widely used in materials characterization. In this work, we briefly introduce the main concepts related to this technique such as, linear and non-linear viscoelasticity, relaxation time, response of material when it ...
Silvana Navarro Cassu, Maria Isabel Felisberti   +1 more
doaj   +1 more source

Lattice structures of Cu-Cr-Zr copper alloy by selective laser melting: Microstructures, mechanical properties and energy absorption

Materials & Design, 2020
Characterized by high thermal-electrical conductivity and reasonable specific strength, lattice structures of copper alloy have great potential in industrial applications.
Zhibo Ma, David Z. Zhang, Fei Liu, Junjie Jiang, Miao Zhao, Tao Zhang   +5 more
doaj   +1 more source

Diffraction and near-zero transmission of flexural phonons at graphene grain boundaries [PDF]

, 2015
Graphene grain boundaries are known to affect phonon transport and thermal conductivity, suggesting that they may be used to engineer the phononic properties of graphene.
Helgee, Edit E., Isacsson, Andreas
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Structural relaxation in amorphous materials under cyclic tension-compression loading

, 2019
The process of structural relaxation in disordered solids subjected to repeated tension-compression loading is studied using molecular dynamics simulations.
Jana, Pritam Kumar, Priezjev, Nikolai V.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Influence of mechanical correction on the geometric and mechanical properties of cold-formed periodic profile fittings

Литьë и металлургия, 2020
The article describes the process of mechanical correction of cold-formed fittings produced in coils on industrial rightsized cutting machines of rotary and roller types.
L. V. Loktionova
doaj   +1 more source

Thermoelastic Properties and Elastocaloric Effect in Rapidly Quenched Ribbons of Ti₂NiCu Alloy in the Amorphous and Crystalline State

Crystals, 2021
The thermoelastic properties and the elastocaloric effect (ECE) were studied in rapidly quenched ribbons of the Ti2NiCu alloy samples in amorphous and crystalline states under periodic mechanical tension with a frequency of up to 50 Hz.
Evgeny Morozov, Dmitry Kuznetsov, Vladimir Kalashnikov, Koledov Victor, Vladimir Shavrov   +4 more
doaj   +1 more source