Results 11 to 20 of about 246,063 (270)

Periodic mechanical stress activates MEK1/2-ERK1/2 mitogenic signals in rat chondrocytes through Src and PLCγ1 [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2011
The mitogenic effects of periodic mechanical stress on chondrocytes have been studied extensively but the mechanisms whereby chondrocytes sense and respond to periodic mechanical stress remain a matter of debate.
Kewei Ren   +9 more
doaj   +4 more sources

Periodic Mechanical Stress Stimulates Cav-1-Dependent IGF-1R Mitogenic Signals in Rat Chondrocytes Through ERK1/2 [PDF]

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: The biological effects of periodic mechanical stress on the mitogenesis of chondrocytes have been studied extensively over the past few years.
Kewei Ren   +6 more
doaj   +3 more sources

Periodic Mechanical Stress Activates PKCδ-Dependent EGFR Mitogenic Signals in Rat Chondrocytes via PI3K-Akt and ERK1/2 [PDF]

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: The present study aimed to analyze the mechanisms by which periodic mechanical stress is translated into biochemical signals, and to verify the important role of signaling molecules including phosphatidylinositol-3-kinase (PI3K)-Akt ...
Peng He   +8 more
doaj   +3 more sources

Periodic mechanical stress enhances rat chondrocyte area expansion and migration through Src-PLCγ1-ERK1/2 signaling

open access: yesEuropean Journal of Cell Biology, 2010
The signal transduction pathways of chondrocyte area expansion and migration under periodic mechanical stress remain a matter of debate. We explore this question by performing cell culture experiments in our self-developed periodic stress field and perfusion culture system.
Luming, Nong   +4 more
openaire   +4 more sources

Impact of Geometry on the Thermal and Mechanical Properties of Periodic Surface Structures: A Numerical Study [PDF]

open access: yesMATEC Web of Conferences, 2022
Periodic Surface Structures (PSS) fabricated via Additive Manufacturing (AM) have recently emerged as being appropriate candidates for high-value engineered structures.
Gawrońska Elżbieta, Dyja Robert
doaj   +1 more source

Glucocorticoid‐sensitive period of corticotroph development—Implications for mechanisms of early life stress

open access: yesJournal of Neuroendocrinology, 2023
Abstract Corticotrophs are intermediaries in the hypothalamic–pituitary–adrenal (HPA) axis, which plays a crucial role in stress response in vertebrates. The HPA axis displays an intricate mode of negative feedback regulation, whereby the peripheral effector, cortisol inhibits the secretion of its upstream regulator ...
Guy Peles   +2 more
openaire   +2 more sources

Theoretical model of homogenized piezoelectric materials with small non-collinear periodic cracks [PDF]

open access: yesFracture and Structural Integrity, 2017
An analytical model for the homogenization of a piezoelectric material with small periodic fissures is proposed on the basis of the method of asymptotic expansions for the elastic displacement, the electric scalar potential and the test functions ...
Jean M. Nianga, D. Marhabi
doaj   +3 more sources

A modified Oster-Murray-Harris mechanical model of morphogenesis [PDF]

open access: yes, 2013
There are two main modeling paradigms for biological pattern formation in developmental biology: chemical prepattern models and cell aggregation models. This paper focuses on an example of a cell aggregation model, the mechanical model developed by Oster,
Benjamin L. Vaughan   +6 more
core   +1 more source

Influence of Uniaxial Tensile Stress on the Mechanical and Piezoelectric Properties of Short-period Ferroelectric Superlattice [PDF]

open access: yesNanoscale Research Letters, 2009
Tetragonal ferroelectric/ferroelectric BaTiO3/PbTiO3 superlattice under uniaxial tensile stress along the c axis is investigated from first principles. We show that the calculated ideal tensile strength is 6.85 GPa and that the superlattice under the loading of uniaxial tensile stress becomes soft along the nonpolar axes.
Wang Chunmei   +3 more
openaire   +4 more sources

Faults Self-Organized by Repeated Earthquakes in a Quasi-Static Antiplane Crack Model [PDF]

open access: yes, 1995
We study a 2D quasi-static discrete {\it crack} anti-plane model of a tectonic plate with long range elastic forces and quenched disorder. The plate is driven at its border and the load is transfered to all elements through elastic forces. This model can
Sornette, Didier, Vanneste, Christian
core   +5 more sources

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