Proteomic Analysis Reveals a New Benefit of Periodic Mechanical Stress on Chondrocytes [PDF]
Background/Aims: In recent years, a variety of studies have been performed to investigate the cellular responses of periodic mechanical stress. In our previous studies, we found that periodic mechanical stress can promote proliferation and matrix ...
Zeng Li +4 more
doaj +3 more sources
Proteomic Analysis Reveals Grb2 as a Key Regulator of Periodic Mechanical Stress Transduction in Chondrocytes [PDF]
Background/Aims: Periodic mechanical stress could significantly promote chondrocyte proliferation and matrix synthesis. However, the mechanisms underlying the ability of chondrocyte detecting and responding to periodic mechanical stimuli have not been ...
Shun Xu +6 more
doaj +3 more sources
Periodic Mechanical Stress Stimulates GIT1-Dependent Mitogenic Signals in Rat Chondrocytes Through ERK1/2 Activity [PDF]
Background/Aims: The mitogenic effects of periodic mechanical stress on chondrocytes have been studied extensively, but the mechanisms whereby chondrocytes sense and respond to mechanical stimuli remain to be determined.
Kewei Ren +6 more
doaj +3 more sources
Integrin β1 Gene Therapy Enhances in Vitro Creation of Tissue-Engineered Cartilage Under Periodic Mechanical Stress [PDF]
Background/Aims: Periodic mechanical stress activates integrin β1-initiated signal pathways to promote chondrocyte proliferation and matrix synthesis. Integrin β1 overexpression has been demonstrated to play important roles in improving the activities ...
Wenwei Liang +9 more
doaj +3 more sources
Cross-polarization coupling in polarization maintaining fiber induced by periodic mechanical stress
One of the applications of polarization maintaining (PM) fibers is the creation of various sensors including level and hydrostatic pressure sensors. An external mechanical stress on a PM fiber causes cross-polarization coupling.
E. E. Kalugin +3 more
doaj +2 more sources
Abstract Corticotrophs are intermediaries in the hypothalamic–pituitary–adrenal (HPA) axis, which plays a crucial role in stress response in vertebrates. The HPA axis displays an intricate mode of negative feedback regulation, whereby the peripheral effector, cortisol inhibits the secretion of its upstream regulator ...
Guy Peles +2 more
openaire +2 more sources
Influence of Uniaxial Tensile Stress on the Mechanical and Piezoelectric Properties of Short-period Ferroelectric Superlattice [PDF]
Tetragonal ferroelectric/ferroelectric BaTiO3/PbTiO3 superlattice under uniaxial tensile stress along the c axis is investigated from first principles. We show that the calculated ideal tensile strength is 6.85 GPa and that the superlattice under the loading of uniaxial tensile stress becomes soft along the nonpolar axes.
Wang Chunmei +3 more
openaire +4 more sources
Effect of Curing Stress and Period on the Mechanical Properties of Cement-Mixed Sand
ABSTRACT Cement mixing is one of the popular ground improvement technologies in geotechnical engineering practice. In order to effectively and confidently design cement-mixed soil structures for specific purposes, its stress-strain behavior needs to be well understood. Though there have been many studies on cement-mixed soils using different types of
RABBI, ABU TAHER MD ZILLUR +3 more
openaire +2 more sources
Assur graphs, marginally jammed packings, and reconfigurable metamaterials
Isostatic frames are mechanical networks that are simultaneously rigid and stress-free. Isostaticity itself is a powerful concept in understanding phase transitions in soft matter and designing mechanical metamaterials.
Jose Ortiz-Tavarez +2 more
doaj +1 more source
Background/Aims: Periodic mechanical stress has been shown to promote extracellular matrix (ECM) synthesis and cell migration of nucleus pulposus (NP) cells, however, the mechanisms need to be fully elucidated.
Gongming Gao +8 more
doaj +1 more source

