Results 101 to 110 of about 1,446,784 (362)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

On odd-periodic orbits in complex planar billiards

open access: yes, 2013
The famous conjecture of V.Ya.Ivrii (1978) says that {\it in every billiard with infinitely-smooth boundary in a Euclidean space the set of periodic orbits has measure zero}. In the present paper we study the complex version of Ivrii's conjecture for odd-
Glutsyuk, Alexey
core   +2 more sources

A Note on Almost Periodic Points and Minimal Sets in T1- and T2-Spaces

open access: yesDiscrete Dynamics in Nature and Society, 2008
We show that (1) there exist almost periodic orbits in T2-spaces of which the closures are not minimal sets; (2) there exist minimal sets in locally compact T1-spaces which are not compact; (3) there exist almost periodic orbits in T2-spaces of which the
Jie-Hua Mai, Xin-He Liu
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Displaced solar sail orbits : dynamics and applications [PDF]

open access: yes, 2010
We consider displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar sail. These highly non-Keplerian orbits are achieved using an extremely small sail acceleration.
McInnes, Colin R., Simo, Jules
core   +1 more source

Semiclassical Quantisation Using Diffractive Orbits

open access: yes, 1995
Diffraction, in the context of semiclassical mechanics, describes the manner in which quantum mechanics smooths over discontinuities in the classical mechanics.
A. Sommerfeld   +19 more
core   +2 more sources

Periodic orbits, superintegrability, and Bertrand’s theorem

open access: yesAIP Advances, 2020
Periodic orbits are the key for understanding classical Hamiltonian systems. As we show here, they are the clue for understanding Bertrand’s result relating the boundedness, flatness, and periodicity of orbits with the functional form of the potentials ...
R. P. Martínez-y-Romero   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Solar sail trajectories at the Earth-Moon Lagrange points [PDF]

open access: yes, 2008
Paper presented during Session 3, Orbital Dynamics, Symposium C1, Astrodynamics, Paper Number 13. This paper investigates displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar ...
McInnes, Colin R., Simo, Jules
core  

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