Results 91 to 100 of about 3,159 (265)

StarCLR: Contrastive Learning Representation for Astronomical Light Curves

open access: yesThe Astrophysical Journal
With the rapid development of time-domain surveys, the availability of large-scale light-curve data offers new opportunities for studying stellar evolution and variable-star classification, while simultaneously posing challenges for feature extraction ...
Junyao Ding   +9 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Revisiting γ-ray Orbital Modulation in the Redback Millisecond Pulsar PSR J2039−5617

open access: yesThe Astrophysical Journal
PSR J2039−5617 is a redback millisecond pulsar binary system consisting of a compact star with a mass of 1.1–1.6 M _⊙ and a low-mass companion of 0.15–0.22 M _⊙ .
Mengqing Zhang   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The Optical Photometric Variability of Herbig Ae/Be Stars from TESS

open access: yesThe Astrophysical Journal
We have carried out a photometric time domain study of 188 intermediate-mass young stars observed in Full Frame Image mode with the Transiting Exoplanet Survey Satellite (TESS) satellite over the first 3.3 yr of its mission. The majority of these targets
Ann Marie Cody   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Is Crater II Disrupting?

open access: yesThe Astronomical Journal
Crater II (CraII) is a very intriguing low surface brightness and extended galaxy in the vicinity of our Galaxy. Motivated by its huge area and the number of RR Lyrae stars (RRLSs) detected near to its core, we performed a follow-up campaign to get deep ...
A. Katherina Vivas   +7 more
doaj   +1 more source

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