Results 91 to 100 of about 72,602 (290)

Automated classification of variable stars for All-Sky Automated Survey 1-2 data [PDF]

open access: yes, 2017
With the advent of surveys generating multi-epoch photometry and the discovery of large numbers of variable stars, the classification of these stars has to be automatic.
Blake, C., Eyer, L.
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

ZTF IC 10 Variable Catalog

open access: yesThe Astrophysical Journal Supplement Series
To study how massive variable stars affect their environment, we search for variability among Zwicky Transient Facility (ZTF) sources located within the optical extent of the nearby starburst galaxy IC 10.
Zehao Jin, Joseph D. Gelfand
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

On X-ray pulsations in beta Cephei-type variables

open access: yes, 2015
Beta Cephei-type variables are early B-type stars that are characterized by oscillations observable in their optical light curves. At least one Beta Cep-variable also shows periodic variability in X-rays.
Balona, L.   +6 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A Comparison of Best Fits Obtained in White Dwarf Asteroseismology Using the WDEC and the LPCODE

open access: yesThe Astrophysical Journal
We perform the asteroseismic fitting of four DAVs using a grid of WDEC models with chemical profiles that closely mimic those of the LPCODE models and compare them with published asteroseismic fitting results using the LPCODE.
Agnès Bischoff-Kim
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Constraints from Parallaxes and Average Period Spacings in the Asteroseismic Study of Eight Hydrogen-atmosphere Pulsating White Dwarfs

open access: yesThe Astrophysical Journal
With space missions such as Kepler, TESS, and Gaia, we have a wealth of data on pulsating white dwarfs that can be leveraged in white dwarf asteroseismology. We address the question of the proportion of white dwarfs with thin hydrogen layers versus those
Agnès Bischoff-Kim, Keaton J. Bell
doaj   +1 more source

Automated classification of periodic variable stars{Improved methodology for the automated classification of periodic variable stars}

open access: yes, 2011
11 pages, 6 figures Accepted for publication in ...
Blomme, J.   +13 more
openaire   +2 more sources

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